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Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening.
Mouhsine H, Guillemain H, Moreau G, Fourati N, Zerrouki C, Baron B, Desallais L, Gizzi P, Ben Nasr N, Perrier J, Ratsimandresy R, Spadoni JL, Do H, England P, Montes M, Zagury JF. Mouhsine H, et al. Among authors: gizzi p. Sci Rep. 2017 Jun 13;7(1):3424. doi: 10.1038/s41598-017-03427-z. Sci Rep. 2017. PMID: 28611375 Free PMC article.
Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.
Regenass P, Abboud D, Daubeuf F, Lehalle C, Gizzi P, Riché S, Hachet-Haas M, Rohmer F, Gasparik V, Boeglin D, Haiech J, Knehans T, Rognan D, Heissler D, Marsol C, Villa P, Galzi JL, Hibert M, Frossard N, Bonnet D. Regenass P, et al. Among authors: gizzi p. J Med Chem. 2018 Sep 13;61(17):7671-7686. doi: 10.1021/acs.jmedchem.8b00657. Epub 2018 Aug 28. J Med Chem. 2018. PMID: 30106292
Small neutralizing molecules to inhibit actions of the chemokine CXCL12.
Hachet-Haas M, Balabanian K, Rohmer F, Pons F, Franchet C, Lecat S, Chow KY, Dagher R, Gizzi P, Didier B, Lagane B, Kellenberger E, Bonnet D, Baleux F, Haiech J, Parmentier M, Frossard N, Arenzana-Seisdedos F, Hibert M, Galzi JL. Hachet-Haas M, et al. Among authors: gizzi p. J Biol Chem. 2008 Aug 22;283(34):23189-99. doi: 10.1074/jbc.M803947200. Epub 2008 Jun 13. J Biol Chem. 2008. PMID: 18556651 Free article.
[Quality control of chemical libraries].
Galzi JL, Ruggiu F, Gizzi P, Didier B. Galzi JL, et al. Among authors: gizzi p. Med Sci (Paris). 2015 Jun-Jul;31(6-7):660-6. doi: 10.1051/medsci/20153106020. Epub 2015 Jul 7. Med Sci (Paris). 2015. PMID: 26152171 Free article. Review. French.
New fluorescein precursors for live bacteria detection.
Guilini C, Baehr C, Schaeffer E, Gizzi P, Rufi F, Haiech J, Weiss E, Bonnet D, Galzi JL. Guilini C, et al. Among authors: gizzi p. Anal Chem. 2015 Sep 1;87(17):8858-66. doi: 10.1021/acs.analchem.5b02100. Epub 2015 Aug 20. Anal Chem. 2015. PMID: 26260548
24 results