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Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides.
Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, Gizzi P, Erakovic Haber V, Bencetic Mihaljevic V, Tavcar B, Portelius E, Pannee J, Blennow K, Zetterberg H, Garbis SD, Auvray P, Gerber H, Fraering J, Fraering PC, Meijer L. Cam M, et al. Among authors: gizzi p. J Alzheimers Dis. 2018;62(4):1663-1681. doi: 10.3233/JAD-170875. J Alzheimers Dis. 2018. PMID: 29504531 Free PMC article.
Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening.
Mouhsine H, Guillemain H, Moreau G, Fourati N, Zerrouki C, Baron B, Desallais L, Gizzi P, Ben Nasr N, Perrier J, Ratsimandresy R, Spadoni JL, Do H, England P, Montes M, Zagury JF. Mouhsine H, et al. Among authors: gizzi p. Sci Rep. 2017 Jun 13;7(1):3424. doi: 10.1038/s41598-017-03427-z. Sci Rep. 2017. PMID: 28611375 Free PMC article.
Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1H-pyrazole-5-carboxylate as an HIV-1 replication inhibitor.
Fichez J, Soulie C, Le Corre L, Sayon S, Priet S, Alvarez K, Delelis O, Gizzi P, Prestat G, Gravier-Pelletier C, Marcelin AG, Calvez V, Busca P. Fichez J, et al. Among authors: gizzi p. RSC Med Chem. 2020 Apr 27;11(5):577-582. doi: 10.1039/d0md00025f. eCollection 2020 May 1. RSC Med Chem. 2020. PMID: 33479659 Free PMC article.
Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.
Regenass P, Abboud D, Daubeuf F, Lehalle C, Gizzi P, Riché S, Hachet-Haas M, Rohmer F, Gasparik V, Boeglin D, Haiech J, Knehans T, Rognan D, Heissler D, Marsol C, Villa P, Galzi JL, Hibert M, Frossard N, Bonnet D. Regenass P, et al. Among authors: gizzi p. J Med Chem. 2018 Sep 13;61(17):7671-7686. doi: 10.1021/acs.jmedchem.8b00657. Epub 2018 Aug 28. J Med Chem. 2018. PMID: 30106292
24 results