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Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy.
Capogrosso RF, Mantuano P, Uaesoontrachoon K, Cozzoli A, Giustino A, Dow T, Srinivassane S, Filipovic M, Bell C, Vandermeulen J, Massari AM, De Bellis M, Conte E, Pierno S, Camerino GM, Liantonio A, Nagaraju K, De Luca A. Capogrosso RF, et al. Among authors: giustino a. FASEB J. 2018 Feb;32(2):1025-1043. doi: 10.1096/fj.201700182RRR. Epub 2018 Jan 3. FASEB J. 2018. PMID: 29097503 Free PMC article.
Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points.
Capogrosso RF, Mantuano P, Cozzoli A, Sanarica F, Massari AM, Conte E, Fonzino A, Giustino A, Rolland JF, Quaranta A, De Bellis M, Camerino GM, Grange RW, De Luca A. Capogrosso RF, et al. Among authors: giustino a. J Appl Physiol (1985). 2017 Apr 1;122(4):828-843. doi: 10.1152/japplphysiol.00776.2015. Epub 2017 Jan 5. J Appl Physiol (1985). 2017. PMID: 28057817 Free article.
Proof-of-concept validation of the mechanism of action of Src tyrosine kinase inhibitors in dystrophic mdx mouse muscle: in vivo and in vitro studies.
Sanarica F, Mantuano P, Conte E, Cozzoli A, Capogrosso RF, Giustino A, Cutrignelli A, Cappellari O, Rolland JF, De Bellis M, Denora N, Camerino GM, De Luca A. Sanarica F, et al. Among authors: giustino a. Pharmacol Res. 2019 Jul;145:104260. doi: 10.1016/j.phrs.2019.104260. Epub 2019 May 3. Pharmacol Res. 2019. PMID: 31059789
Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase.
Cozzoli A, Liantonio A, Conte E, Cannone M, Massari AM, Giustino A, Scaramuzzi A, Pierno S, Mantuano P, Capogrosso RF, Camerino GM, De Luca A. Cozzoli A, et al. Among authors: giustino a. Am J Physiol Cell Physiol. 2014 Oct 1;307(7):C634-47. doi: 10.1152/ajpcell.00372.2013. Epub 2014 Jul 30. Am J Physiol Cell Physiol. 2014. PMID: 25080489 Free PMC article.
Assessment of resveratrol, apocynin and taurine on mechanical-metabolic uncoupling and oxidative stress in a mouse model of duchenne muscular dystrophy: A comparison with the gold standard, α-methyl prednisolone.
Capogrosso RF, Cozzoli A, Mantuano P, Camerino GM, Massari AM, Sblendorio VT, De Bellis M, Tamma R, Giustino A, Nico B, Montagnani M, De Luca A. Capogrosso RF, et al. Among authors: giustino a. Pharmacol Res. 2016 Apr;106:101-113. doi: 10.1016/j.phrs.2016.02.016. Epub 2016 Feb 27. Pharmacol Res. 2016. PMID: 26930420
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin.
Camerino GM, De Bellis M, Conte E, Liantonio A, Musaraj K, Cannone M, Fonzino A, Giustino A, De Luca A, Romano R, Camerino C, Laghezza A, Loiodice F, Desaphy JF, Conte Camerino D, Pierno S. Camerino GM, et al. Among authors: giustino a. Toxicol Appl Pharmacol. 2016 Sep 1;306:36-46. doi: 10.1016/j.taap.2016.06.032. Epub 2016 Jul 1. Toxicol Appl Pharmacol. 2016. PMID: 27377005
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia.
Conte E, Camerino GM, Mele A, De Bellis M, Pierno S, Rana F, Fonzino A, Caloiero R, Rizzi L, Bresciani E, Ben Haj Salah K, Fehrentz JA, Martinez J, Giustino A, Mariggiò MA, Coluccia M, Tricarico D, Lograno MD, De Luca A, Torsello A, Conte D, Liantonio A. Conte E, et al. Among authors: giustino a. J Cachexia Sarcopenia Muscle. 2017 Jun;8(3):386-404. doi: 10.1002/jcsm.12185. Epub 2017 Mar 10. J Cachexia Sarcopenia Muscle. 2017. PMID: 28294567 Free PMC article.
Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ.
Camerino GM, Bouchè M, De Bellis M, Cannone M, Liantonio A, Musaraj K, Romano R, Smeriglio P, Madaro L, Giustino A, De Luca A, Desaphy JF, Camerino DC, Pierno S. Camerino GM, et al. Among authors: giustino a. Pflugers Arch. 2014 Dec;466(12):2215-28. doi: 10.1007/s00424-014-1495-1. Epub 2014 Mar 20. Pflugers Arch. 2014. PMID: 24643479
37 results