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Page 1
Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators.
Ivanova Bencheva L, Donnici L, Ferrante L, Prandi A, Sinisi R, De Matteo M, Randazzo P, Conti M, Di Lucia P, Bono E, Giustini L, Vittoria Orsale M, Patsilinakos A, Monteagudo E, Iannacone M, Summa V, Guidotti LG, De Francesco R, Di Fabio R. Ivanova Bencheva L, et al. Among authors: giustini l. Bioorg Med Chem Lett. 2022 Oct 1;73:128904. doi: 10.1016/j.bmcl.2022.128904. Epub 2022 Jul 19. Bioorg Med Chem Lett. 2022. PMID: 35868496
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming.
Bénéchet AP, De Simone G, Di Lucia P, Cilenti F, Barbiera G, Le Bert N, Fumagalli V, Lusito E, Moalli F, Bianchessi V, Andreata F, Zordan P, Bono E, Giustini L, Bonilla WV, Bleriot C, Kunasegaran K, Gonzalez-Aseguinolaza G, Pinschewer DD, Kennedy PTF, Naldini L, Kuka M, Ginhoux F, Cantore A, Bertoletti A, Ostuni R, Guidotti LG, Iannacone M. Bénéchet AP, et al. Among authors: giustini l. Nature. 2019 Oct;574(7777):200-205. doi: 10.1038/s41586-019-1620-6. Epub 2019 Oct 2. Nature. 2019. PMID: 31582858 Free PMC article.
Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells.
De Giovanni M, Cutillo V, Giladi A, Sala E, Maganuco CG, Medaglia C, Di Lucia P, Bono E, Cristofani C, Consolo E, Giustini L, Fiore A, Eickhoff S, Kastenmüller W, Amit I, Kuka M, Iannacone M. De Giovanni M, et al. Among authors: giustini l. Nat Immunol. 2020 Mar;21(3):321-330. doi: 10.1038/s41590-020-0596-6. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066949 Free PMC article.
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming.
De Simone G, Andreata F, Bleriot C, Fumagalli V, Laura C, Garcia-Manteiga JM, Di Lucia P, Gilotto S, Ficht X, De Ponti FF, Bono EB, Giustini L, Ambrosi G, Mainetti M, Zordan P, Bénéchet AP, Ravà M, Chakarov S, Moalli F, Bajenoff M, Guidotti LG, Ginhoux F, Iannacone M. De Simone G, et al. Among authors: giustini l. Immunity. 2021 Sep 14;54(9):2089-2100.e8. doi: 10.1016/j.immuni.2021.05.005. Epub 2021 Aug 31. Immunity. 2021. PMID: 34469774 Free PMC article.
COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models.
Conforti A, Marra E, Palombo F, Roscilli G, Ravà M, Fumagalli V, Muzi A, Maffei M, Luberto L, Lione L, Salvatori E, Compagnone M, Pinto E, Pavoni E, Bucci F, Vitagliano G, Stoppoloni D, Pacello ML, Cappelletti M, Ferrara FF, D'Acunto E, Chiarini V, Arriga R, Nyska A, Di Lucia P, Marotta D, Bono E, Giustini L, Sala E, Perucchini C, Paterson J, Ryan KA, Challis AR, Matusali G, Colavita F, Caselli G, Criscuolo E, Clementi N, Mancini N, Groß R, Seidel A, Wettstein L, Münch J, Donnici L, Conti M, De Francesco R, Kuka M, Ciliberto G, Castilletti C, Capobianchi MR, Ippolito G, Guidotti LG, Rovati L, Iannacone M, Aurisicchio L. Conforti A, et al. Among authors: giustini l. Mol Ther. 2022 Jan 5;30(1):311-326. doi: 10.1016/j.ymthe.2021.09.011. Epub 2021 Sep 20. Mol Ther. 2022. PMID: 34547465 Free PMC article.
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion.
Fumagalli V, Ravà M, Marotta D, Di Lucia P, Laura C, Sala E, Grillo M, Bono E, Giustini L, Perucchini C, Mainetti M, Sessa A, Garcia-Manteiga JM, Donnici L, Manganaro L, Delbue S, Broccoli V, De Francesco R, D'Adamo P, Kuka M, Guidotti LG, Iannacone M. Fumagalli V, et al. Among authors: giustini l. Sci Immunol. 2022 Jan 28;7(67):eabl9929. doi: 10.1126/sciimmunol.abl9929. Epub 2022 Jan 28. Sci Immunol. 2022. PMID: 34812647 Free PMC article.
Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability.
Fumagalli V, Venzin V, Di Lucia P, Moalli F, Ficht X, Ambrosi G, Giustini L, Andreata F, Grillo M, Magini D, Ravà M, Friedrich C, Fontenot JD, Bousso P, Gilmore SA, Khan S, Baca M, Vivier E, Gasteiger G, Kuka M, Guidotti LG, Iannacone M. Fumagalli V, et al. Among authors: giustini l. Sci Immunol. 2022 Feb 25;7(68):eabi6112. doi: 10.1126/sciimmunol.abi6112. Epub 2022 Feb 25. Sci Immunol. 2022. PMID: 35213210
CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus.
Andreata F, Moynihan KD, Fumagalli V, Di Lucia P, Pappas DC, Kawashima K, Ni I, Bessette PH, Perucchini C, Bono E, Giustini L, Nguyen HC, Chin SM, Yeung YA, Gibbs CS, Djuretic I, Iannacone M. Andreata F, et al. Among authors: giustini l. Sci Transl Med. 2024 Jan 10;16(729):eadi1572. doi: 10.1126/scitranslmed.adi1572. Epub 2024 Jan 10. Sci Transl Med. 2024. PMID: 38198572
Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination.
Fumagalli V, Ravà M, Marotta D, Di Lucia P, Bono EB, Giustini L, De Leo F, Casalgrandi M, Monteleone E, Mouro V, Malpighi C, Perucchini C, Grillo M, De Palma S, Donnici L, Marchese S, Conti M, Muramatsu H, Perlman S, Pardi N, Kuka M, De Francesco R, Bianchi ME, Guidotti LG, Iannacone M. Fumagalli V, et al. Among authors: giustini l. Nat Immunol. 2024 Apr;25(4):633-643. doi: 10.1038/s41590-024-01787-z. Epub 2024 Mar 14. Nat Immunol. 2024. PMID: 38486021 Free PMC article.
Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells.
Mooney AH, Draper SL, Burn OK, Anderson RJ, Compton BJ, Tang C, Farrand KJ, Di Lucia P, Ravà M, Fumagalli V, Giustini L, Bono E, Godfrey DI, Heath WR, Yuan W, Chisari FV, Guidotti LG, Iannacone M, Sidney J, Sette A, Gulab SA, Painter GF, Hermans IF. Mooney AH, et al. Among authors: giustini l. JHEP Rep. 2024 Feb 12;6(5):101038. doi: 10.1016/j.jhepr.2024.101038. eCollection 2024 May. JHEP Rep. 2024. PMID: 38694959 Free PMC article.
59 results