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Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma.
Carrabotta M, Laginestra MA, Durante G, Mancarella C, Landuzzi L, Parra A, Ruzzi F, Toracchio L, De Feo A, Giusti V, Pasello M, Righi A, Lollini PL, Palmerini E, Donati DM, Manara MC, Scotlandi K. Carrabotta M, et al. Among authors: giusti v. Cancer Res. 2022 Feb 15;82(4):708-720. doi: 10.1158/0008-5472.CAN-21-1222. Cancer Res. 2022. PMID: 34903601 Free PMC article.
HER2 isoforms co-expression differently tunes mammary tumor phenotypes affecting onset, vasculature and therapeutic response.
Palladini A, Nicoletti G, Lamolinara A, Dall'Ora M, Balboni T, Ianzano ML, Laranga R, Landuzzi L, Giusti V, Ceccarelli C, Santini D, Taffurelli M, Di Oto E, Asioli S, Amici A, Pupa SM, De Giovanni C, Tagliabue E, Iezzi M, Nanni P, Lollini PL. Palladini A, et al. Among authors: giusti v. Oncotarget. 2017 Apr 13;8(33):54444-54458. doi: 10.18632/oncotarget.17088. eCollection 2017 Aug 15. Oncotarget. 2017. PMID: 28903354 Free PMC article.
Virus-like particle display of HER2 induces potent anti-cancer responses.
Palladini A, Thrane S, Janitzek CM, Pihl J, Clemmensen SB, de Jongh WA, Clausen TM, Nicoletti G, Landuzzi L, Penichet ML, Balboni T, Ianzano ML, Giusti V, Theander TG, Nielsen MA, Salanti A, Lollini PL, Nanni P, Sander AF. Palladini A, et al. Among authors: giusti v. Oncoimmunology. 2018 Jan 5;7(3):e1408749. doi: 10.1080/2162402X.2017.1408749. eCollection 2018. Oncoimmunology. 2018. PMID: 29399414 Free PMC article.
Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations.
Nanni P, Landuzzi L, Manara MC, Righi A, Nicoletti G, Cristalli C, Pasello M, Parra A, Carrabotta M, Ferracin M, Palladini A, Ianzano ML, Giusti V, Ruzzi F, Magnani M, Donati DM, Picci P, Lollini PL, Scotlandi K. Nanni P, et al. Among authors: giusti v. Sci Rep. 2019 Aug 21;9(1):12174. doi: 10.1038/s41598-019-48634-y. Sci Rep. 2019. PMID: 31434953 Free PMC article.
Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft.
Landuzzi L, Palladini A, Ceccarelli C, Asioli S, Nicoletti G, Giusti V, Ruzzi F, Ianzano ML, Scalambra L, Laranga R, Balboni T, Arigoni M, Olivero M, Calogero RA, De Giovanni C, Dall'Ora M, Di Oto E, Santini D, Foschini MP, Cucchi MC, Zanotti S, Taffurelli M, Nanni P, Lollini PL. Landuzzi L, et al. Among authors: giusti v. Sci Rep. 2021 Jan 15;11(1):1563. doi: 10.1038/s41598-021-81085-y. Sci Rep. 2021. PMID: 33452364 Free PMC article.
Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells.
Mancarella C, Giusti V, Caldoni G, Laginestra MA, Parra A, Toracchio L, Giordano G, Roncuzzi L, Piazzi M, Blalock W, Columbaro M, De Feo A, Scotlandi K. Mancarella C, et al. Among authors: giusti v. Cancer Gene Ther. 2023 Sep;30(9):1285-1295. doi: 10.1038/s41417-023-00637-8. Epub 2023 Jun 23. Cancer Gene Ther. 2023. PMID: 37353558 Free PMC article.
Parkinson's Disease-Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance.
Streubel-Gallasch L, Giusti V, Sandre M, Tessari I, Plotegher N, Giusto E, Masato A, Iovino L, Battisti I, Arrigoni G, Shimshek D, Greggio E, Tremblay ME, Bubacco L, Erlandsson A, Civiero L. Streubel-Gallasch L, et al. Among authors: giusti v. Mol Neurobiol. 2021 Jul;58(7):3119-3140. doi: 10.1007/s12035-021-02327-8. Epub 2021 Feb 24. Mol Neurobiol. 2021. PMID: 33629273 Free PMC article.
Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson's disease.
Iovino L, Giusti V, Pischedda F, Giusto E, Plotegher N, Marte A, Battisti I, Di Iacovo A, Marku A, Piccoli G, Bandopadhyay R, Perego C, Bonifacino T, Bonanno G, Roseti C, Bossi E, Arrigoni G, Bubacco L, Greggio E, Hilfiker S, Civiero L. Iovino L, et al. Among authors: giusti v. Acta Neuropathol. 2022 Jul;144(1):81-106. doi: 10.1007/s00401-022-02437-0. Epub 2022 May 21. Acta Neuropathol. 2022. PMID: 35596783 Free PMC article.
184 results