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Page 1
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2.
Ferrisi R, Polini B, Ricardi C, Gado F, Mohamed KA, Baron G, Faiella S, Poli G, Rapposelli S, Saccomanni G, Aldini G, Chiellini G, Laprairie RB, Manera C, Ortore G. Ferrisi R, et al. Among authors: saccomanni g. Int J Mol Sci. 2023 Jan 21;24(3):2135. doi: 10.3390/ijms24032135. Int J Mol Sci. 2023. PMID: 36768458 Free PMC article.
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R).
Ferrisi R, Gado F, Polini B, Ricardi C, Mohamed KA, Stevenson LA, Ortore G, Rapposelli S, Saccomanni G, Pertwee RG, Laprairie RB, Manera C, Chiellini G. Ferrisi R, et al. Among authors: saccomanni g. Front Chem. 2022 Sep 27;10:984069. doi: 10.3389/fchem.2022.984069. eCollection 2022. Front Chem. 2022. PMID: 36238097 Free PMC article.
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands.
Gado F, Ferrisi R, Polini B, Mohamed KA, Ricardi C, Lucarini E, Carpi S, Domenichini F, Stevenson LA, Rapposelli S, Saccomanni G, Nieri P, Ortore G, Pertwee RG, Ghelardini C, Di Cesare Mannelli L, Chiellini G, Laprairie RB, Manera C. Gado F, et al. Among authors: saccomanni g. J Med Chem. 2022 Jul 28;65(14):9918-9938. doi: 10.1021/acs.jmedchem.2c00582. Epub 2022 Jul 18. J Med Chem. 2022. PMID: 35849804 Free PMC article.
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells.
Gado F, Ferrisi R, Di Somma S, Napolitano F, Mohamed KA, Stevenson LA, Rapposelli S, Saccomanni G, Portella G, Pertwee RG, Laprairie RB, Malfitano AM, Manera C. Gado F, et al. Among authors: saccomanni g. Molecules. 2022 May 7;27(9):3019. doi: 10.3390/molecules27093019. Molecules. 2022. PMID: 35566369 Free PMC article.
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor.
Bertini S, Chicca A, Gado F, Arena C, Nieri D, Digiacomo M, Saccomanni G, Zhao P, Abood ME, Macchia M, Gertsch J, Manera C. Bertini S, et al. Among authors: saccomanni g. Bioorg Med Chem. 2017 Dec 15;25(24):6427-6434. doi: 10.1016/j.bmc.2017.10.015. Epub 2017 Oct 16. Bioorg Med Chem. 2017. PMID: 29079014 Free PMC article.
45 results