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A bacteriophage mimic of the bacterial nucleoid-associated protein Fis.
Biochem J. 2020 Apr 17;477(7):1345-1362. doi: 10.1042/BCJ20200146.
Biochem J. 2020.
PMID: 32207815
Free PMC article.
The Tomato Nucleotide-binding Leucine-rich Repeat Immune Receptor I-2 Couples DNA-binding to Nucleotide-binding Domain Nucleotide Exchange.
Fenyk S, Dixon CH, Gittens WH, Townsend PD, Sharples GJ, Pålsson LO, Takken FL, Cann MJ.
Fenyk S, et al. Among authors: gittens wh.
J Biol Chem. 2016 Jan 15;291(3):1137-47. doi: 10.1074/jbc.M115.698589. Epub 2015 Nov 24.
J Biol Chem. 2016.
PMID: 26601946
Free PMC article.
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A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome.
Gittens WH, Johnson DJ, Allison RM, Cooper TJ, Thomas H, Neale MJ.
Gittens WH, et al.
Nat Commun. 2019 Oct 24;10(1):4846. doi: 10.1038/s41467-019-12802-5.
Nat Commun. 2019.
PMID: 31649282
Free PMC article.
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Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.
Hanzlikova H, Gittens W, Krejcikova K, Zeng Z, Caldecott KW.
Hanzlikova H, et al.
Nucleic Acids Res. 2017 Mar 17;45(5):2546-2557. doi: 10.1093/nar/gkw1246.
Nucleic Acids Res. 2017.
PMID: 27965414
Free PMC article.
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XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
Hoch NC, Hanzlikova H, Rulten SL, Tétreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, Staras K, Mancini GM, McKinnon PJ, Wang ZQ, Wagner JD; Care4Rare Canada Consortium; Yoon G, Caldecott KW.
Hoch NC, et al.
Nature. 2017 Jan 5;541(7635):87-91. doi: 10.1038/nature20790. Epub 2016 Dec 21.
Nature. 2017.
PMID: 28002403
Free PMC article.
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XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.
Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW.
Demin AA, et al.
Mol Cell. 2021 Jul 15;81(14):3018-3030.e5. doi: 10.1016/j.molcel.2021.05.009. Epub 2021 Jun 7.
Mol Cell. 2021.
PMID: 34102106
Free PMC article.
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Meiotic prophase length modulates Tel1-dependent DNA double-strand break interference.
López Ruiz LM, Johnson D, Gittens WH, Brown GGB, Allison RM, Neale MJ.
López Ruiz LM, et al. Among authors: gittens wh.
PLoS Genet. 2024 Mar 1;20(3):e1011140. doi: 10.1371/journal.pgen.1011140. eCollection 2024 Mar.
PLoS Genet. 2024.
PMID: 38427688
Free PMC article.
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