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LPS-neutralizing peptides reduce outer membrane vesicle-induced inflammatory responses.
Pfalzgraff A, Correa W, Heinbockel L, Schromm AB, Lübow C, Gisch N, Martinez-de-Tejada G, Brandenburg K, Weindl G. Pfalzgraff A, et al. Among authors: gisch n. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1503-1513. doi: 10.1016/j.bbalip.2019.05.018. Epub 2019 Jun 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31163264
Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares.
Azzouz DF, Chen Z, Izmirly PM, Chen LA, Li Z, Zhang C, Mieles D, Trujillo K, Heguy A, Pironti A, Putzel GG, Schwudke D, Fenyo D, Buyon JP, Alekseyenko AV, Gisch N, Silverman GJ. Azzouz DF, et al. Among authors: gisch n. Ann Rheum Dis. 2023 Oct;82(10):1315-1327. doi: 10.1136/ard-2023-223929. Epub 2023 Jun 26. Ann Rheum Dis. 2023. PMID: 37365013 Free PMC article.
Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides.
Martinez de Tejada G, Heinbockel L, Ferrer-Espada R, Heine H, Alexander C, Bárcena-Varela S, Goldmann T, Correa W, Wiesmüller KH, Gisch N, Sánchez-Gómez S, Fukuoka S, Schürholz T, Gutsmann T, Brandenburg K. Martinez de Tejada G, et al. Among authors: gisch n. Sci Rep. 2015 Sep 22;5:14292. doi: 10.1038/srep14292. Sci Rep. 2015. PMID: 26390973 Free PMC article.
The human LL-37 peptide exerts antimicrobial activity against Legionella micdadei interacting with membrane phospholipids.
Palusińska-Szysz M, Jurak M, Gisch N, Waldow F, Zehethofer N, Nehls C, Schwudke D, Koper P, Mazur A. Palusińska-Szysz M, et al. Among authors: gisch n. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jun;1867(6):159138. doi: 10.1016/j.bbalip.2022.159138. Epub 2022 Feb 26. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 35231605
Characterization of phospholipid-modified lung surfactant in vitro and in a neonatal ARDS model reveals anti-inflammatory potential and surfactant lipidome signatures.
Kupsch S, Eggers LF, Spengler D, Gisch N, Goldmann T, Fehrenbach H, Stichtenoth G, Krause MF, Schwudke D, Schromm AB. Kupsch S, et al. Among authors: gisch n. Eur J Pharm Sci. 2022 Aug 1;175:106216. doi: 10.1016/j.ejps.2022.106216. Epub 2022 May 23. Eur J Pharm Sci. 2022. PMID: 35618202 Free article.
The lipid composition of Legionella dumoffii membrane modulates the interaction with Galleria mellonella apolipophorin III.
Palusińska-Szysz M, Zdybicka-Barabas A, Reszczyńska E, Luchowski R, Kania M, Gisch N, Waldow F, Mak P, Danikiewicz W, Gruszecki WI, Cytryńska M. Palusińska-Szysz M, et al. Among authors: gisch n. Biochim Biophys Acta. 2016 Jul;1861(7):617-29. doi: 10.1016/j.bbalip.2016.04.011. Epub 2016 Apr 17. Biochim Biophys Acta. 2016. PMID: 27094351
62 results