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The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor.
Girola N, Matsuo AL, Figueiredo CR, Massaoka MH, Farias CF, Arruda DC, Azevedo RA, Monteiro HP, Resende-Lara PT, Cunha RL, Polonelli L, Travassos LR. Girola N, et al. Peptides. 2016 Nov;85:1-15. doi: 10.1016/j.peptides.2016.08.006. Epub 2016 Aug 26. Peptides. 2016. PMID: 27575453
Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma.
Figueiredo CR, Azevedo RA, Mousdell S, Resende-Lara PT, Ireland L, Santos A, Girola N, Cunha RLOR, Schmid MC, Polonelli L, Travassos LR, Mielgo A. Figueiredo CR, et al. Among authors: girola n. Front Immunol. 2018 May 23;9:1132. doi: 10.3389/fimmu.2018.01132. eCollection 2018. Front Immunol. 2018. PMID: 29875777 Free PMC article.
Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo.
de Azevedo RA, Figueiredo CR, Ferreira AK, Matsuo AL, Massaoka MH, Girola N, Auada AV, Farias CF, Pasqualoto KF, Rodrigues CP, Barbuto JA, Levy D, Bydlowski SP, de Sá-Junior PL, Travassos LR, Lebrun I. de Azevedo RA, et al. Among authors: girola n. Peptides. 2015 Jun;68:113-9. doi: 10.1016/j.peptides.2014.09.024. Epub 2014 Oct 14. Peptides. 2015. PMID: 25305549
Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo.
Girola N, Figueiredo CR, Farias CF, Azevedo RA, Ferreira AK, Teixeira SF, Capello TM, Martins EG, Matsuo AL, Travassos LR, Lago JH. Girola N, et al. Biochem Biophys Res Commun. 2015 Nov 27;467(4):928-34. doi: 10.1016/j.bbrc.2015.10.041. Epub 2015 Oct 16. Biochem Biophys Res Commun. 2015. PMID: 26471302
19 results