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Page 1
Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation.
Kroth H, Ansaloni A, Varisco Y, Jan A, Sreenivasachary N, Rezaei-Ghaleh N, Giriens V, Lohmann S, López-Deber MP, Adolfsson O, Pihlgren M, Paganetti P, Froestl W, Nagel-Steger L, Willbold D, Schrader T, Zweckstetter M, Pfeifer A, Lashuel HA, Muhs A. Kroth H, et al. Among authors: giriens v. J Biol Chem. 2012 Oct 5;287(41):34786-800. doi: 10.1074/jbc.M112.357665. Epub 2012 Aug 13. J Biol Chem. 2012. PMID: 22891248 Free PMC article.
Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases.
Hickman DT, López-Deber MP, Ndao DM, Silva AB, Nand D, Pihlgren M, Giriens V, Madani R, St-Pierre A, Karastaneva H, Nagel-Steger L, Willbold D, Riesner D, Nicolau C, Baldus M, Pfeifer A, Muhs A. Hickman DT, et al. Among authors: giriens v. J Biol Chem. 2011 Apr 22;286(16):13966-76. doi: 10.1074/jbc.M110.186338. Epub 2011 Feb 22. J Biol Chem. 2011. PMID: 21343310 Free PMC article.
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice.
Muhs A, Hickman DT, Pihlgren M, Chuard N, Giriens V, Meerschman C, van der Auwera I, van Leuven F, Sugawara M, Weingertner MC, Bechinger B, Greferath R, Kolonko N, Nagel-Steger L, Riesner D, Brady RO, Pfeifer A, Nicolau C. Muhs A, et al. Among authors: giriens v. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9810-5. doi: 10.1073/pnas.0703137104. Epub 2007 May 21. Proc Natl Acad Sci U S A. 2007. PMID: 17517595 Free PMC article.
An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.
Belichenko PV, Madani R, Rey-Bellet L, Pihlgren M, Becker A, Plassard A, Vuillermot S, Giriens V, Nosheny RL, Kleschevnikov AM, Valletta JS, Bengtsson SK, Linke GR, Maloney MT, Hickman DT, Reis P, Granet A, Mlaki D, Lopez-Deber MP, Do L, Singhal N, Masliah E, Pearn ML, Pfeifer A, Muhs A, Mobley WC. Belichenko PV, et al. Among authors: giriens v. PLoS One. 2016 Mar 29;11(3):e0152471. doi: 10.1371/journal.pone.0152471. eCollection 2016. PLoS One. 2016. PMID: 27023444 Free PMC article.
TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell-independent isotype switch in mice.
Pihlgren M, Silva AB, Madani R, Giriens V, Waeckerle-Men Y, Fettelschoss A, Hickman DT, López-Deber MP, Ndao DM, Vukicevic M, Buccarello AL, Gafner V, Chuard N, Reis P, Piorkowska K, Pfeifer A, Kündig TM, Muhs A, Johansen P. Pihlgren M, et al. Among authors: giriens v. Blood. 2013 Jan 3;121(1):85-94. doi: 10.1182/blood-2012-02-413831. Epub 2012 Nov 8. Blood. 2013. PMID: 23144170 Free article.
An amyloid beta vaccine that safely drives immunity to a key pathological species in Alzheimer's disease: pyroglutamate amyloid beta.
Vukicevic M, Fiorini E, Siegert S, Carpintero R, Rincon-Restrepo M, Lopez-Deber P, Piot N, Ayer M, Rentero I, Babolin C, Bravo-Veyrat S, Giriens V, Morici C, Beuzelin M, Gesbert A, Rivot S, Depretti S, Donati P, Streffer J, Pfeifer A, Kosco-Vilbois MH. Vukicevic M, et al. Among authors: giriens v. Brain Commun. 2022 Feb 4;4(1):fcac022. doi: 10.1093/braincomms/fcac022. eCollection 2022. Brain Commun. 2022. PMID: 35479516 Free PMC article.