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Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary.
Brundu S, Napolitano V, Franzolin G, Lo Cascio E, Mastrantonio R, Sardo G, Cascardi E, Verginelli F, Sarnataro S, Gambardella G, Pisacane A, Arcovito A, Boccaccio C, Comoglio PM, Giraudo E, Tamagnone L. Brundu S, et al. Among authors: giraudo e. EMBO Mol Med. 2023 Mar 8;15(3):e16104. doi: 10.15252/emmm.202216104. Epub 2023 Feb 1. EMBO Mol Med. 2023. PMID: 36722641 Free PMC article.
HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.
Qiu Y, Maione F, Capano S, Meda C, Picconi O, Brundu S, Pisacane A, Sapino A, Palladino C, Barillari G, Monini P, Bussolino F, Ensoli B, Sgadari C, Giraudo E. Qiu Y, et al. Among authors: giraudo e. Mol Cancer Ther. 2020 Dec;19(12):2476-2489. doi: 10.1158/1535-7163.MCT-20-0055. Epub 2020 Oct 20. Mol Cancer Ther. 2020. PMID: 33082275
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability.
Gioelli N, Neilson LJ, Wei N, Villari G, Chen W, Kuhle B, Ehling M, Maione F, Willox S, Brundu S, Avanzato D, Koulouras G, Mazzone M, Giraudo E, Yang XL, Valdembri D, Zanivan S, Serini G. Gioelli N, et al. Among authors: giraudo e. Nat Commun. 2022 Jul 20;13(1):4188. doi: 10.1038/s41467-022-31904-1. Nat Commun. 2022. PMID: 35858913 Free PMC article.
Correction: Ponzo et al. Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression. Cancers 2022, 14, 4265.
Ponzo M, Debesset A, Cossutta M, Chalabi-Dchar M, Houppe C, Pilon C, Nicolas-Boluda A, Meunier S, Raineri F, Thiolat A, Nicolle R, Maione F, Brundu S, Cojocaru CF, Bouvet P, Bousquet C, Gazeau F, Tournigand C, Courty J, Giraudo E, Cohen JL, Cascone I. Ponzo M, et al. Among authors: giraudo e. Cancers (Basel). 2022 Dec 14;14(24):6160. doi: 10.3390/cancers14246160. Cancers (Basel). 2022. PMID: 36551754 Free PMC article.
A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.
Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G. Gioelli N, et al. Among authors: giraudo e. Sci Transl Med. 2018 May 23;10(442):eaah4807. doi: 10.1126/scitranslmed.aah4807. Sci Transl Med. 2018. PMID: 29794061 Free article.
Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression.
Ponzo M, Debesset A, Cossutta M, Chalabi-Dchar M, Houppe C, Pilon C, Nicolas-Boluda A, Meunier S, Raineri F, Thiolat A, Nicolle R, Maione F, Brundu S, Cojocaru CF, Bouvet P, Bousquet C, Gazeau F, Tournigand C, Courty J, Giraudo E, Cohen JL, Cascone I. Ponzo M, et al. Among authors: giraudo e. Cancers (Basel). 2022 Aug 31;14(17):4265. doi: 10.3390/cancers14174265. Cancers (Basel). 2022. PMID: 36077801 Free PMC article.
62 results