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Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease.
Sánchez Montero JM, Agis-Torres A, Solano D, Söllhuber M, Fernandez M, Villaro W, Gómez-Cañas M, García-Arencibia M, Fernández-Ruiz J, Egea J, Martín MI, Girón R. Sánchez Montero JM, et al. Among authors: giron r. Eur J Pharmacol. 2021 Mar 15;895:173875. doi: 10.1016/j.ejphar.2021.173875. Epub 2021 Jan 15. Eur J Pharmacol. 2021. PMID: 33460612
Chromenopyrazoles: non-psychoactive and selective CB₁ cannabinoid agonists with peripheral antinociceptive properties.
Cumella J, Hernández-Folgado L, Girón R, Sánchez E, Morales P, Hurst DP, Gómez-Cañas M, Gómez-Ruiz M, Pinto DC, Goya P, Reggio PH, Martin MI, Fernández-Ruiz J, Silva AM, Jagerovic N. Cumella J, et al. Among authors: giron r. ChemMedChem. 2012 Mar 5;7(3):452-63. doi: 10.1002/cmdc.201100568. Epub 2012 Feb 2. ChemMedChem. 2012. PMID: 22302767 Free PMC article.
Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease.
González-Naranjo P, Pérez-Macias N, Campillo NE, Pérez C, Arán VJ, Girón R, Sánchez-Robles E, Martín MI, Gómez-Cañas M, García-Arencibia M, Fernández-Ruiz J, Páez JA. González-Naranjo P, et al. Among authors: giron r. Eur J Med Chem. 2014 Feb 12;73:56-72. doi: 10.1016/j.ejmech.2013.11.026. Epub 2013 Dec 7. Eur J Med Chem. 2014. PMID: 24378710
Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results.
Fernández-Fernández C, Callado LF, Girón R, Sánchez E, Erdozain AM, López-Moreno JA, Morales P, Rodríguez de Fonseca F, Fernández-Ruiz J, Goya P, Meana JJ, Martín MI, Jagerovic N. Fernández-Fernández C, et al. Among authors: giron r. Drug Des Devel Ther. 2014 Feb 20;8:263-77. doi: 10.2147/DDDT.S55045. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 24591816 Free PMC article.
Discovery of Potent Dual PPARα Agonists/CB1 Ligands.
Pérez-Fernández R, Fresno N, Macías-González M, Elguero J, Decara J, Girón R, Rodríguez-Álvarez A, Martín MI, Rodríguez de Fonseca F, Goya P. Pérez-Fernández R, et al. Among authors: giron r. ACS Med Chem Lett. 2011 Sep 16;2(11):793-7. doi: 10.1021/ml200091q. eCollection 2011 Nov 10. ACS Med Chem Lett. 2011. PMID: 24936232 Free PMC article.
Indazolylketones as new multitarget cannabinoid drugs.
González-Naranjo P, Pérez-Macias N, Pérez C, Roca C, Vaca G, Girón R, Sánchez-Robles E, Martín-Fontelles MI, de Ceballos ML, Martin-Requero A, Campillo NE, Páez JA. González-Naranjo P, et al. Among authors: giron r. Eur J Med Chem. 2019 Mar 15;166:90-107. doi: 10.1016/j.ejmech.2019.01.030. Epub 2019 Jan 17. Eur J Med Chem. 2019. PMID: 30685536
New cannabinoid receptor antagonists as pharmacological tool.
González-Naranjo P, Pérez C, Girón R, Sánchez-Robles EM, Martín-Fontelles MI, Carrillo-López N, Martín-Vírgala J, Naves M, Campillo NE, Páez JA. González-Naranjo P, et al. Among authors: giron r. Bioorg Med Chem. 2020 Oct 1;28(19):115672. doi: 10.1016/j.bmc.2020.115672. Epub 2020 Jul 29. Bioorg Med Chem. 2020. PMID: 32912440
165 results