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Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function.
Van Der Steen N, Keller K, Dekker H, Porcelli L, Honeywell RJ, Van Meerloo J, Musters RJP, Kathmann I, Frampton AE, Liu DSK, Ruijtenbeek R, Rolfo C, Pauwels P, Giovannetti E, Peters GJ. Van Der Steen N, et al. Among authors: giovannetti e. J Cell Physiol. 2020 Nov;235(11):8085-8097. doi: 10.1002/jcp.29463. Epub 2020 Jan 20. J Cell Physiol. 2020. PMID: 31960422 Free PMC article.
Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.
Giovannetti E, Lemos C, Tekle C, Smid K, Nannizzi S, Rodriguez JA, Ricciardi S, Danesi R, Giaccone G, Peters GJ. Giovannetti E, et al. Mol Pharmacol. 2008 Apr;73(4):1290-300. doi: 10.1124/mol.107.042382. Epub 2008 Jan 10. Mol Pharmacol. 2008. PMID: 18187583
401 results