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Highly Potent and Selective Dopamine D4 Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma.
Pavletić P, Semeano A, Yano H, Bonifazi A, Giorgioni G, Piergentili A, Quaglia W, Sabbieti MG, Agas D, Santoni G, Pallini R, Ricci-Vitiani L, Sabato E, Vistoli G, Del Bello F. Pavletić P, et al. Among authors: giorgioni g. J Med Chem. 2022 Sep 22;65(18):12124-12139. doi: 10.1021/acs.jmedchem.2c00840. Epub 2022 Sep 13. J Med Chem. 2022. PMID: 36098685 Free PMC article.
Synthesis and preliminary pharmacological evaluation of 5-hydroxy- and 5,6-dihydroxy-1,2,3,7,12,12a-hexahydrobenzo[5,6]cyclohepta[1,2,3-ij]isoquinoline derivatives as dopamine receptor ligands.
Cingolani GM, Di Stefano A, Napolitani F, Mosciatti B, Giorgioni G, Cinone N, Brunetti L, Luisi G, Michelotto B, Orlando G, Costa B, Lucacchini A, Martini C, Claudi F. Cingolani GM, et al. Among authors: giorgioni g. Bioorg Med Chem. 2001 Jun;9(6):1447-58. doi: 10.1016/s0968-0896(01)00016-5. Bioorg Med Chem. 2001. PMID: 11408163
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists.
Di Stefano A, Sozio P, Cacciatore I, Cocco A, Giorgioni G, Costa B, Montali M, Lucacchini A, Martini C, Spoto G, Di Pietrantonio F, Di Matteo E, Pinnen F. Di Stefano A, et al. Among authors: giorgioni g. J Med Chem. 2005 Apr 7;48(7):2646-54. doi: 10.1021/jm040889k. J Med Chem. 2005. PMID: 15801855
Glycosyl and polyalcoholic prodrugs of lonidamine.
Giorgioni G, Ruggieri S, Di Stefano A, Sozio P, Cinque B, Di Marzio L, Santoni G, Claudi F. Giorgioni G, et al. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2445-50. doi: 10.1016/j.bmcl.2008.02.046. Epub 2008 Mar 5. Bioorg Med Chem Lett. 2008. PMID: 18321702
Dopamine D5 receptors: a challenge to medicinal chemists.
Giorgioni G, Piergentili A, Ruggieri S, Quaglia W. Giorgioni G, et al. Mini Rev Med Chem. 2008 Sep;8(10):976-95. doi: 10.2174/138955708785740661. Mini Rev Med Chem. 2008. PMID: 18782049 Review.
52 results