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Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity.
Guidetti L, Zappia A, Scalvini L, Ferrari FR, Giorgio C, Castelli R, Galvani F, Vacondio F, Rivara S, Mor M, Urbinati C, Rusnati M, Tognolini M, Lodola A. Guidetti L, et al. Among authors: giorgio c. J Chem Inf Model. 2023 Nov 13;63(21):6900-6911. doi: 10.1021/acs.jcim.3c01064. Epub 2023 Nov 1. J Chem Inf Model. 2023. PMID: 37910792 Free PMC article.
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.
Incerti M, Tognolini M, Russo S, Pala D, Giorgio C, Hassan-Mohamed I, Noberini R, Pasquale EB, Vicini P, Piersanti S, Rivara S, Barocelli E, Mor M, Lodola A. Incerti M, et al. Among authors: giorgio c. J Med Chem. 2013 Apr 11;56(7):2936-47. doi: 10.1021/jm301890k. Epub 2013 Mar 22. J Med Chem. 2013. PMID: 23489211 Free PMC article.
Δ(5)-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system.
Castelli R, Tognolini M, Vacondio F, Incerti M, Pala D, Callegari D, Bertoni S, Giorgio C, Hassan-Mohamed I, Zanotti I, Bugatti A, Rusnati M, Festuccia C, Rivara S, Barocelli E, Mor M, Lodola A. Castelli R, et al. Among authors: giorgio c. Eur J Med Chem. 2015 Oct 20;103:312-24. doi: 10.1016/j.ejmech.2015.08.048. Epub 2015 Aug 29. Eur J Med Chem. 2015. PMID: 26363867
Metadynamics for Perspective Drug Design: Computationally Driven Synthesis of New Protein-Protein Interaction Inhibitors Targeting the EphA2 Receptor.
Incerti M, Russo S, Callegari D, Pala D, Giorgio C, Zanotti I, Barocelli E, Vicini P, Vacondio F, Rivara S, Castelli R, Tognolini M, Lodola A. Incerti M, et al. Among authors: giorgio c. J Med Chem. 2017 Jan 26;60(2):787-796. doi: 10.1021/acs.jmedchem.6b01642. Epub 2017 Jan 5. J Med Chem. 2017. PMID: 28005388
Ephrin or not? Six tough questions on Eph targeting.
Giorgio C, Zanotti I, Lodola A, Tognolini M. Giorgio C, et al. Expert Opin Ther Targets. 2020 May;24(5):403-415. doi: 10.1080/14728222.2020.1745187. Epub 2020 Mar 26. Expert Opin Ther Targets. 2020. PMID: 32197575 Review.
318 results