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An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.
LaMarche NM, Hegde S, Park MD, Maier BB, Troncoso L, Le Berichel J, Hamon P, Belabed M, Mattiuz R, Hennequin C, Chin T, Reid AM, Reyes-Torres I, Nemeth E, Zhang R, Olson OC, Doroshow DB, Rohs NC, Gomez JE, Veluswamy R, Hall N, Venturini N, Ginhoux F, Liu Z, Buckup M, Figueiredo I, Roudko V, Miyake K, Karasuyama H, Gonzalez-Kozlova E, Gnjatic S, Passegué E, Kim-Schulze S, Brown BD, Hirsch FR, Kim BS, Marron TU, Merad M. LaMarche NM, et al. Among authors: ginhoux f. Nature. 2024 Jan;625(7993):166-174. doi: 10.1038/s41586-023-06797-9. Epub 2023 Dec 6. Nature. 2024. PMID: 38057662 Clinical Trial.
Langerhans cells arise from monocytes in vivo.
Ginhoux F, Tacke F, Angeli V, Bogunovic M, Loubeau M, Dai XM, Stanley ER, Randolph GJ, Merad M. Ginhoux F, et al. Nat Immunol. 2006 Mar;7(3):265-73. doi: 10.1038/ni1307. Epub 2006 Jan 29. Nat Immunol. 2006. PMID: 16444257 Free PMC article.
The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics.
Ledgerwood LG, Lal G, Zhang N, Garin A, Esses SJ, Ginhoux F, Merad M, Peche H, Lira SA, Ding Y, Yang Y, He X, Schuchman EH, Allende ML, Ochando JC, Bromberg JS. Ledgerwood LG, et al. Among authors: ginhoux f. Nat Immunol. 2008 Jan;9(1):42-53. doi: 10.1038/ni1534. Epub 2007 Nov 25. Nat Immunol. 2008. PMID: 18037890
360 results