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Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor-Positive Breast Cancer.
Whittle JR, Vaillant F, Surgenor E, Policheni AN, Giner G, Capaldo BD, Chen HR, Liu HK, Dekkers JF, Sachs N, Clevers H, Fellowes A, Green T, Xu H, Fox SB, Herold MJ, Smyth GK, Gray DHD, Visvader JE, Lindeman GJ. Whittle JR, et al. Among authors: giner g. Clin Cancer Res. 2020 Aug 1;26(15):4120-4134. doi: 10.1158/1078-0432.CCR-19-1872. Epub 2020 Apr 3. Clin Cancer Res. 2020. PMID: 32245900
RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.
Nolan E, Vaillant F, Branstetter D, Pal B, Giner G, Whitehead L, Lok SW, Mann GB; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab); Rohrbach K, Huang LY, Soriano R, Smyth GK, Dougall WC, Visvader JE, Lindeman GJ. Nolan E, et al. Among authors: giner g. Nat Med. 2016 Aug;22(8):933-9. doi: 10.1038/nm.4118. Epub 2016 Jun 20. Nat Med. 2016. PMID: 27322743
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer.
Merino D, Whittle JR, Vaillant F, Serrano A, Gong JN, Giner G, Maragno AL, Chanrion M, Schneider E, Pal B, Li X, Dewson G, Gräsel J, Liu K, Lalaoui N, Segal D, Herold MJ, Huang DCS, Smyth GK, Geneste O, Lessene G, Visvader JE, Lindeman GJ. Merino D, et al. Among authors: giner g. Sci Transl Med. 2017 Aug 2;9(401):eaam7049. doi: 10.1126/scitranslmed.aam7049. Sci Transl Med. 2017. PMID: 28768804
Targeting triple-negative breast cancers with the Smac-mimetic birinapant.
Lalaoui N, Merino D, Giner G, Vaillant F, Chau D, Liu L, Kratina T, Pal B, Whittle JR, Etemadi N, Berthelet J, Gräsel J, Hall C, Ritchie ME, Ernst M, Smyth GK, Vaux DL, Visvader JE, Lindeman GJ, Silke J. Lalaoui N, et al. Among authors: giner g. Cell Death Differ. 2020 Oct;27(10):2768-2780. doi: 10.1038/s41418-020-0541-0. Epub 2020 Apr 27. Cell Death Differ. 2020. PMID: 32341449 Free PMC article.
Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance.
Deng Y, Diepstraten ST, Potts MA, Giner G, Trezise S, Ng AP, Healey G, Kane SR, Cooray A, Behrens K, Heidersbach A, Kueh AJ, Pal M, Wilcox S, Tai L, Alexander WS, Visvader JE, Nutt SL, Strasser A, Haley B, Zhao Q, Kelly GL, Herold MJ. Deng Y, et al. Among authors: giner g. Nat Commun. 2022 Aug 12;13(1):4739. doi: 10.1038/s41467-022-32485-9. Nat Commun. 2022. PMID: 35961968 Free PMC article.
Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance.
Deng Y, Diepstraten ST, Potts MA, Giner G, Trezise S, Ng AP, Healey G, Kane SR, Cooray A, Behrens K, Heidersbach A, Kueh AJ, Pal M, Wilcox S, Tai L, Alexander WS, Visvader JE, Nutt SL, Strasser A, Haley B, Zhao Q, Kelly GL, Herold MJ. Deng Y, et al. Among authors: giner g. Nat Commun. 2022 Aug 25;13(1):5007. doi: 10.1038/s41467-022-32817-9. Nat Commun. 2022. PMID: 36008403 Free PMC article. No abstract available.
Review of the existing maximum residue levels for pyriproxyfen according to Article 12 of Regulation (EC) No 396/2005.
European Food Safety Authority (EFSA); Bellisai G, Bernasconi G, Brancato A, Cabrera LC, Castellan I, Ferreira L, Giner G, Greco L, Jarrah S, Leuschner R, Magrans JO, Miron I, Nave S, Pedersen R, Reich H, Robinson T, Ruocco S, Santos M, Scarlato AP, Theobald A, Verani A. European Food Safety Authority (EFSA), et al. Among authors: giner g. EFSA J. 2022 Nov 30;20(11):e07617. doi: 10.2903/j.efsa.2022.7617. eCollection 2022 Nov. EFSA J. 2022. PMID: 36465667 Free PMC article.
Targeted review of maximum residues levels (MRLs) for haloxyfop-P.
European Food Safety Authority (EFSA); Bellisai G, Bernasconi G, Brancato A, Cabrera LC, Castellan I, Del Aguila M, Ferreira L, Giner G, Greco L, Jarrah S, Leuschner R, Magrans JO, Miron I, Nave S, Pedersen R, Reich H, Robinson T, Ruocco S, Santos M, Scarlato AP, Theobald A, Verani A. European Food Safety Authority (EFSA), et al. Among authors: giner g. EFSA J. 2022 Nov 18;20(11):e07658. doi: 10.2903/j.efsa.2022.7658. eCollection 2022 Nov. EFSA J. 2022. PMID: 36415856 Free PMC article.
67 results