Altered levels of plasma neuron-derived exosomes and their cargo proteins characterize acute and chronic mild traumatic brain injury.
Goetzl EJ, Elahi FM, Mustapic M, Kapogiannis D, Pryhoda M, Gilmore A, Gorgens KA, Davidson B, Granholm AC, Ledreux A.
Goetzl EJ, et al. Among authors: gilmore a.
FASEB J. 2019 Apr;33(4):5082-5088. doi: 10.1096/fj.201802319R. Epub 2019 Jan 3.
FASEB J. 2019.
PMID: 30605353
Free PMC article.
Plasma concentrations of NDEs, assessed by counts and levels of extracted exosome marker CD81, were significantly depressed by a mean of 45% in acute mTBI ( P < 0.0001), but not chronic mTBI, compared with controls. ...J., Elahi, F. M., Mustapic, M., Kapogiannis, D., Pr
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Plasma concentrations of NDEs, assessed by counts and levels of extracted exosome marker CD81, were significantly depressed by a mean …