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Engineering antibody therapeutics.
Chiu ML, Gilliland GL. Chiu ML, et al. Among authors: gilliland gl. Curr Opin Struct Biol. 2016 Jun;38:163-73. doi: 10.1016/j.sbi.2016.07.012. Epub 2016 Aug 12. Curr Opin Struct Biol. 2016. PMID: 27525816 Free article. Review.
Structural diversity in a human antibody germline library.
Teplyakov A, Obmolova G, Malia TJ, Luo J, Muzammil S, Sweet R, Almagro JC, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. MAbs. 2016 Aug-Sep;8(6):1045-63. doi: 10.1080/19420862.2016.1190060. Epub 2016 May 21. MAbs. 2016. PMID: 27210805 Free PMC article.
Crystal structure of CD27 in complex with a neutralizing noncompeting antibody.
Teplyakov A, Obmolova G, Malia TJ, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. Acta Crystallogr F Struct Biol Commun. 2017 May 1;73(Pt 5):294-299. doi: 10.1107/S2053230X17005957. Epub 2017 Apr 26. Acta Crystallogr F Struct Biol Commun. 2017. PMID: 28471362 Free PMC article.
A coiled conformation of amyloid-β recognized by antibody C706.
Teplyakov A, Obmolova G, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. Alzheimers Res Ther. 2017 Aug 22;9(1):66. doi: 10.1186/s13195-017-0296-0. Alzheimers Res Ther. 2017. PMID: 28830506 Free PMC article.
Structural insights into chemokine CCL17 recognition by antibody M116.
Teplyakov A, Obmolova G, Gilliland GL. Teplyakov A, et al. Among authors: gilliland gl. Biochem Biophys Rep. 2017 Dec 9;13:27-31. doi: 10.1016/j.bbrep.2017.11.005. eCollection 2018 Mar. Biochem Biophys Rep. 2017. PMID: 29264403 Free PMC article.
Structure-based engineering of a monoclonal antibody for improved solubility.
Wu SJ, Luo J, O'Neil KT, Kang J, Lacy ER, Canziani G, Baker A, Huang M, Tang QM, Raju TS, Jacobs SA, Teplyakov A, Gilliland GL, Feng Y. Wu SJ, et al. Among authors: gilliland gl. Protein Eng Des Sel. 2010 Aug;23(8):643-51. doi: 10.1093/protein/gzq037. Epub 2010 Jun 11. Protein Eng Des Sel. 2010. PMID: 20543007
177 results