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Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.
Pomel V, Klicic J, Covini D, Church DD, Shaw JP, Roulin K, Burgat-Charvillon F, Valognes D, Camps M, Chabert C, Gillieron C, Françon B, Perrin D, Leroy D, Gretener D, Nichols A, Vitte PA, Carboni S, Rommel C, Schwarz MK, Rückle T. Pomel V, et al. Among authors: gillieron c. J Med Chem. 2006 Jun 29;49(13):3857-71. doi: 10.1021/jm0601598. J Med Chem. 2006. PMID: 16789742
Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.
Maundrell K, Antonsson B, Magnenat E, Camps M, Muda M, Chabert C, Gillieron C, Boschert U, Vial-Knecht E, Martinou JC, Arkinstall S. Maundrell K, et al. Among authors: gillieron c. J Biol Chem. 1997 Oct 3;272(40):25238-42. doi: 10.1074/jbc.272.40.25238. J Biol Chem. 1997. PMID: 9312139 Free article.
The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding and enzymatic specificity.
Muda M, Theodosiou A, Gillieron C, Smith A, Chabert C, Camps M, Boschert U, Rodrigues N, Davies K, Ashworth A, Arkinstall S. Muda M, et al. Among authors: gillieron c. J Biol Chem. 1998 Apr 10;273(15):9323-9. doi: 10.1074/jbc.273.15.9323. J Biol Chem. 1998. PMID: 9535927 Free article.
We have reported recently that the dual specificity mitogen-activated protein kinase phosphatase-3 (MKP-3) elicits highly selective inactivation of the extracellular signal-regulated kinase (ERK) class of mitogen-activated protein (MAP) kinases (Muda, M., Theodosiou, A., Rodrigue …
We have reported recently that the dual specificity mitogen-activated protein kinase phosphatase-3 (MKP-3) elicits highly selective inactiva …
35 results