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HLA-E-restricted SARS-CoV-2-specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation.
Yang H, Sun H, Brackenridge S, Zhuang X, Wing PAC, Quastel M, Walters L, Garner L, Wang B, Yao X, Felce SL, Peng Y, Moore S, Peeters BWA, Rei M, Canto Gomes J, Tomas A, Davidson A, Semple MG, Turtle LCW, Openshaw PJM, Baillie JK, Mentzer AJ, Klenerman P; ISARIC4C Investigators; Borrow P, Dong T, McKeating JA, Gillespie GM, McMichael AJ. Yang H, et al. Among authors: gillespie gm. Sci Immunol. 2023 Jun 30;8(84):eabl8881. doi: 10.1126/sciimmunol.abl8881. Epub 2023 Jun 30. Sci Immunol. 2023. PMID: 37390223
Human immunodeficiency virus type 1- and cytomegalovirus-specific cytotoxic T lymphocytes can persist at high frequency for prolonged periods in the absence of circulating peripheral CD4(+) T cells.
Spiegel HM, Ogg GS, DeFalcon E, Sheehy ME, Monard S, Haslett PA, Gillespie G, Donahoe SM, Pollack H, Borkowsky W, McMichael AJ, Nixon DF. Spiegel HM, et al. J Virol. 2000 Jan;74(2):1018-22. doi: 10.1128/jvi.74.2.1018-1022.2000. J Virol. 2000. PMID: 10623767 Free PMC article.
Cytotoxic T lymphocytes recognize structurally diverse, clade-specific and cross-reactive peptides in human immunodeficiency virus type-1 gag through HLA-B53.
Dorrell L, Willcox BE, Jones EY, Gillespie G, Njai H, Sabally S, Jaye A, DeGleria K, Rostron T, Lepin E, McMichael A, Whittle H, Rowland-Jones S. Dorrell L, et al. Eur J Immunol. 2001 Jun;31(6):1747-56. doi: 10.1002/1521-4141(200106)31:6<1747::aid-immu1747>3.0.co;2-l. Eur J Immunol. 2001. PMID: 11385619 Free article.
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, Papagno L, Ogg GS, King A, Lechner F, Spina CA, Little S, Havlir DV, Richman DD, Gruener N, Pape G, Waters A, Easterbrook P, Salio M, Cerundolo V, McMichael AJ, Rowland-Jones SL. Appay V, et al. Among authors: gillespie gm. Nat Med. 2002 Apr;8(4):379-85. doi: 10.1038/nm0402-379. Nat Med. 2002. PMID: 11927944
77 results