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An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.
Shih HH, Tu C, Cao W, Klein A, Ramsey R, Fennell BJ, Lambert M, Ní Shúilleabháin D, Autin B, Kouranova E, Laxmanan S, Braithwaite S, Wu L, Ait-Zahra M, Milici AJ, Dumin JA, LaVallie ER, Arai M, Corcoran C, Paulsen JE, Gill D, Cunningham O, Bard J, Mosyak L, Finlay WJ. Shih HH, et al. Among authors: gill d. J Biol Chem. 2012 Dec 28;287(53):44425-34. doi: 10.1074/jbc.M112.415935. Epub 2012 Nov 12. J Biol Chem. 2012. PMID: 23148212 Free PMC article.
Fundamental characteristics of the immunoglobulin VH repertoire of chickens in comparison with those of humans, mice, and camelids.
Wu L, Oficjalska K, Lambert M, Fennell BJ, Darmanin-Sheehan A, Ní Shúilleabháin D, Autin B, Cummins E, Tchistiakova L, Bloom L, Paulsen J, Gill D, Cunningham O, Finlay WJ. Wu L, et al. Among authors: gill d. J Immunol. 2012 Jan 1;188(1):322-33. doi: 10.4049/jimmunol.1102466. Epub 2011 Nov 30. J Immunol. 2012. PMID: 22131336
Comprehensive interrogation of a minimalist synthetic CDR-H3 library and its ability to generate antibodies with therapeutic potential.
Mahon CM, Lambert MA, Glanville J, Wade JM, Fennell BJ, Krebs MR, Armellino D, Yang S, Liu X, O'Sullivan CM, Autin B, Oficjalska K, Bloom L, Paulsen J, Gill D, Damelin M, Cunningham O, Finlay WJ. Mahon CM, et al. Among authors: gill d. J Mol Biol. 2013 May 27;425(10):1712-30. doi: 10.1016/j.jmb.2013.02.015. Epub 2013 Feb 19. J Mol Biol. 2013. PMID: 23429058 Clinical Trial.
Oligomerization is required for the activity of recombinant soluble LOX-1.
Cao W, Calabro V, Root A, Yan G, Lam K, Olland S, Sanford J, Robak A, Zollner R, Lu Z, Ait-Zahra M, Agostinelli R, Tchistiakova L, Gill D, Harnish D, Paulsen J, Shih HH. Cao W, et al. Among authors: gill d. FEBS J. 2009 Sep;276(17):4909-20. doi: 10.1111/j.1742-4658.2009.07190.x. Epub 2009 Jul 31. FEBS J. 2009. PMID: 19664054 Free article.
Atypical antigen recognition mode of a shark immunoglobulin new antigen receptor (IgNAR) variable domain characterized by humanization and structural analysis.
Kovalenko OV, Olland A, Piché-Nicholas N, Godbole A, King D, Svenson K, Calabro V, Müller MR, Barelle CJ, Somers W, Gill DS, Mosyak L, Tchistiakova L. Kovalenko OV, et al. Among authors: gill ds. J Biol Chem. 2013 Jun 14;288(24):17408-19. doi: 10.1074/jbc.M112.435289. Epub 2013 Apr 30. J Biol Chem. 2013. PMID: 23632026 Free PMC article.
Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
Finlay WJ, Cunningham O, Lambert MA, Darmanin-Sheehan A, Liu X, Fennell BJ, Mahon CM, Cummins E, Wade JM, O'Sullivan CM, Tan XY, Piche N, Pittman DD, Paulsen J, Tchistiakova L, Kodangattil S, Gill D, Hufton SE. Finlay WJ, et al. Among authors: gill d. J Mol Biol. 2009 May 8;388(3):541-58. doi: 10.1016/j.jmb.2009.03.019. Epub 2009 Mar 13. J Mol Biol. 2009. PMID: 19285987
1,856 results