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Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia.
Menendez-Gonzalez JB, Vukovic M, Abdelfattah A, Saleh L, Almotiri A, Thomas LA, Agirre-Lizaso A, Azevedo A, Menezes AC, Tornillo G, Edkins S, Kong K, Giles P, Anjos-Afonso F, Tonks A, Boyd AS, Kranc KR, Rodrigues NP. Menendez-Gonzalez JB, et al. Among authors: giles p. Stem Cell Reports. 2019 Aug 13;13(2):291-306. doi: 10.1016/j.stemcr.2019.07.005. Epub 2019 Aug 1. Stem Cell Reports. 2019. PMID: 31378673 Free PMC article.
Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.
Guitart AV, Panagopoulou TI, Villacreces A, Vukovic M, Sepulveda C, Allen L, Carter RN, van de Lagemaat LN, Morgan M, Giles P, Sas Z, Gonzalez MV, Lawson H, Paris J, Edwards-Hicks J, Schaak K, Subramani C, Gezer D, Armesilla-Diaz A, Wills J, Easterbrook A, Coman D, So CW, O'Carroll D, Vernimmen D, Rodrigues NP, Pollard PJ, Morton NM, Finch A, Kranc KR. Guitart AV, et al. Among authors: giles p. J Exp Med. 2017 Mar 6;214(3):719-735. doi: 10.1084/jem.20161087. Epub 2017 Feb 15. J Exp Med. 2017. PMID: 28202494 Free PMC article.
Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.
Almotiri A, Alzahrani H, Menendez-Gonzalez JB, Abdelfattah A, Alotaibi B, Saleh L, Greene A, Georgiou M, Gibbs A, Alsayari A, Taha S, Thomas LA, Shah D, Edkins S, Giles P, Stemmler MP, Brabletz S, Brabletz T, Boyd AS, Siebzehnrubl FA, Rodrigues NP. Almotiri A, et al. Among authors: giles p. J Clin Invest. 2021 Jan 4;131(1):e129115. doi: 10.1172/JCI129115. J Clin Invest. 2021. PMID: 33108352 Free PMC article.
JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells.
Lawson H, Sepulveda C, van de Lagemaat LN, Durko J, Barile M, Tavosanis A, Georges E, Shmakova A, Timms P, Carter RN, Allen L, Campos J, Vukovic M, Guitart AV, Giles P, O'Shea M, Vernimmen D, Morton NM, Rodrigues NP, Göttgens B, Schofield CJ, Lengeling A, O'Carroll D, Kranc KR. Lawson H, et al. Among authors: giles p. Blood Adv. 2021 Feb 9;5(3):889-899. doi: 10.1182/bloodadvances.2020002702. Blood Adv. 2021. PMID: 33560400 Free PMC article.
Increased oral fibroblast lifespan is telomerase-independent.
Enoch S, Wall I, Peake M, Davies L, Farrier J, Giles P, Baird D, Kipling D, Price P, Moseley R, Thomas D, Stephens P. Enoch S, et al. Among authors: giles p. J Dent Res. 2009 Oct;88(10):916-21. doi: 10.1177/0022034509342979. J Dent Res. 2009. PMID: 19783799
'Young' oral fibroblasts are geno/phenotypically distinct.
Enoch S, Peake MA, Wall I, Davies L, Farrier J, Giles P, Kipling D, Price P, Moseley R, Thomas D, Stephens P. Enoch S, et al. Among authors: giles p. J Dent Res. 2010 Dec;89(12):1407-13. doi: 10.1177/0022034510377796. J Dent Res. 2010. PMID: 21098492
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