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MalDA, Accelerating Malaria Drug Discovery.
Yang T, Ottilie S, Istvan ES, Godinez-Macias KP, Lukens AK, Baragaña B, Campo B, Walpole C, Niles JC, Chibale K, Dechering KJ, Llinás M, Lee MCS, Kato N, Wyllie S, McNamara CW, Gamo FJ, Burrows J, Fidock DA, Goldberg DE, Gilbert IH, Wirth DF, Winzeler EA; Malaria Drug Accelerator Consortium. Yang T, et al. Among authors: gilbert ih. Trends Parasitol. 2021 Jun;37(6):493-507. doi: 10.1016/j.pt.2021.01.009. Epub 2021 Feb 26. Trends Parasitol. 2021. PMID: 33648890 Free PMC article. Review.
Target assessment for antiparasitic drug discovery.
Frearson JA, Wyatt PG, Gilbert IH, Fairlamb AH. Frearson JA, et al. Among authors: gilbert ih. Trends Parasitol. 2007 Dec;23(12):589-95. doi: 10.1016/j.pt.2007.08.019. Epub 2007 Oct 24. Trends Parasitol. 2007. PMID: 17962072 Free PMC article. Review.
β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.
Baragaña B, McCarthy O, Sánchez P, Bosch-Navarrete C, Kaiser M, Brun R, Whittingham JL, Roberts SM, Zhou XX, Wilson KS, Johansson NG, González-Pacanowska D, Gilbert IH. Baragaña B, et al. Among authors: gilbert ih. Bioorg Med Chem. 2011 Apr 1;19(7):2378-91. doi: 10.1016/j.bmc.2011.02.012. Epub 2011 Feb 17. Bioorg Med Chem. 2011. PMID: 21411327
Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase.
Hampton SE, Baragaña B, Schipani A, Bosch-Navarrete C, Musso-Buendía JA, Recio E, Kaiser M, Whittingham JL, Roberts SM, Shevtsov M, Brannigan JA, Kahnberg P, Brun R, Wilson KS, González-Pacanowska D, Johansson NG, Gilbert IH. Hampton SE, et al. Among authors: gilbert ih. ChemMedChem. 2011 Oct 4;6(10):1816-31. doi: 10.1002/cmdc.201100255. ChemMedChem. 2011. PMID: 22049550
Quinol derivatives as potential trypanocidal agents.
Capes A, Patterson S, Wyllie S, Hallyburton I, Collie IT, McCarroll AJ, Stevens MF, Frearson JA, Wyatt PG, Fairlamb AH, Gilbert IH. Capes A, et al. Among authors: gilbert ih. Bioorg Med Chem. 2012 Feb 15;20(4):1607-15. doi: 10.1016/j.bmc.2011.12.018. Epub 2011 Dec 27. Bioorg Med Chem. 2012. PMID: 22264753 Free PMC article.
Discovery and structure-activity relationships of pyrrolone antimalarials.
Murugesan D, Mital A, Kaiser M, Shackleford DM, Morizzi J, Katneni K, Campbell M, Hudson A, Charman SA, Yeates C, Gilbert IH. Murugesan D, et al. Among authors: gilbert ih. J Med Chem. 2013 Apr 11;56(7):2975-90. doi: 10.1021/jm400009c. Epub 2013 Mar 21. J Med Chem. 2013. PMID: 23517371 Free PMC article.
Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.
De Rycker M, Hallyburton I, Thomas J, Campbell L, Wyllie S, Joshi D, Cameron S, Gilbert IH, Wyatt PG, Frearson JA, Fairlamb AH, Gray DW. De Rycker M, et al. Among authors: gilbert ih. Antimicrob Agents Chemother. 2013 Jul;57(7):2913-22. doi: 10.1128/AAC.02398-12. Epub 2013 Apr 9. Antimicrob Agents Chemother. 2013. PMID: 23571538 Free PMC article.
209 results