Gilbert HJ - Search Results

1

Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases.

Vardakou M, Dumon C, Murray JW, Christakopoulos P, Weiner DP, Juge N, Lewis RJ, Gilbert HJ, Flint JE. Vardakou M, et al. Among authors: gilbert hj. J Mol Biol. 2008 Feb 1;375(5):1293-305. doi: 10.1016/j.jmb.2007.11.007. Epub 2007 Nov 12. J Mol Biol. 2008. PMID: 18078955

2

Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition.

Correia MA, Prates JA, Brás J, Fontes CM, Newman JA, Lewis RJ, Gilbert HJ, Flint JE. Correia MA, et al. Among authors: gilbert hj. J Mol Biol. 2008 May 23;379(1):64-72. doi: 10.1016/j.jmb.2008.03.037. Epub 2008 Mar 28. J Mol Biol. 2008. PMID: 18436237

3

Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure.

Dumon C, Varvak A, Wall MA, Flint JE, Lewis RJ, Lakey JH, Morland C, Luginbühl P, Healey S, Todaro T, DeSantis G, Sun M, Parra-Gessert L, Tan X, Weiner DP, Gilbert HJ. Dumon C, et al. Among authors: gilbert hj. J Biol Chem. 2008 Aug 15;283(33):22557-64. doi: 10.1074/jbc.M800936200. Epub 2008 May 30. J Biol Chem. 2008. PMID: 18515360 Free article.

4

Ligand-mediated dimerization of a carbohydrate-binding molecule reveals a novel mechanism for protein-carbohydrate recognition.

Flint J, Nurizzo D, Harding SE, Longman E, Davies GJ, Gilbert HJ, Bolam DN. Flint J, et al. Among authors: gilbert hj. J Mol Biol. 2004 Mar 19;337(2):417-26. doi: 10.1016/j.jmb.2003.12.081. J Mol Biol. 2004. PMID: 15003456

5

A family 10 Thermoascus aurantiacus xylanase utilizes arabinose decorations of xylan as significant substrate specificity determinants.

Vardakou M, Flint J, Christakopoulos P, Lewis RJ, Gilbert HJ, Murray JW. Vardakou M, et al. Among authors: gilbert hj. J Mol Biol. 2005 Oct 7;352(5):1060-7. doi: 10.1016/j.jmb.2005.07.051. J Mol Biol. 2005. PMID: 16140328

6

Probing the structural basis for the difference in thermostability displayed by family 10 xylanases.

Xie H, Flint J, Vardakou M, Lakey JH, Lewis RJ, Gilbert HJ, Dumon C. Xie H, et al. Among authors: gilbert hj. J Mol Biol. 2006 Jun 30;360(1):157-67. doi: 10.1016/j.jmb.2006.05.002. Epub 2006 May 15. J Mol Biol. 2006. PMID: 16762367

7

Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.

Tailford LE, Offen WA, Smith NL, Dumon C, Morland C, Gratien J, Heck MP, Stick RV, Blériot Y, Vasella A, Gilbert HJ, Davies GJ. Tailford LE, et al. Among authors: gilbert hj. Nat Chem Biol. 2008 May;4(5):306-12. doi: 10.1038/nchembio.81. Nat Chem Biol. 2008. PMID: 18408714

8

Regulation of the xylan-degrading apparatus of Cellvibrio japonicus by a novel two-component system.

Emami K, Topakas E, Nagy T, Henshaw J, Jackson KA, Nelson KE, Mongodin EF, Murray JW, Lewis RJ, Gilbert HJ. Emami K, et al. Among authors: gilbert hj. J Biol Chem. 2009 Jan 9;284(2):1086-96. doi: 10.1074/jbc.M805100200. Epub 2008 Oct 15. J Biol Chem. 2009. PMID: 18922794 Free article.

9

Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function.

Montanier C, van Bueren AL, Dumon C, Flint JE, Correia MA, Prates JA, Firbank SJ, Lewis RJ, Grondin GG, Ghinet MG, Gloster TM, Herve C, Knox JP, Talbot BG, Turkenburg JP, Kerovuo J, Brzezinski R, Fontes CM, Davies GJ, Boraston AB, Gilbert HJ. Montanier C, et al. Among authors: gilbert hj. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3065-70. doi: 10.1073/pnas.0808972106. Epub 2009 Feb 13. Proc Natl Acad Sci U S A. 2009. PMID: 19218457 Free PMC article.

10

Understanding how diverse beta-mannanases recognize heterogeneous substrates.

Tailford LE, Ducros VM, Flint JE, Roberts SM, Morland C, Zechel DL, Smith N, Bjørnvad ME, Borchert TV, Wilson KS, Davies GJ, Gilbert HJ. Tailford LE, et al. Among authors: gilbert hj. Biochemistry. 2009 Jul 28;48(29):7009-18. doi: 10.1021/bi900515d. Biochemistry. 2009. PMID: 19441796

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