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RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr-/- mice.
Bijnen M, Beelen N, Wetzels S, Gaar JV, Vroomen M, Wijnands E, Scheijen JL, van de Waarenburg MPH, Gijbels MJ, Cleutjens JP, Biessen EAL, Stehouwer CDA, Schalkwijk CG, Wouters K. Bijnen M, et al. Among authors: gijbels mj. Sci Rep. 2018 Oct 15;8(1):15256. doi: 10.1038/s41598-018-33661-y. Sci Rep. 2018. PMID: 30323247 Free PMC article.
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.
Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lütjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. Bieghs V, et al. Among authors: gijbels mj. PLoS One. 2012;7(1):e30668. doi: 10.1371/journal.pone.0030668. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295101 Free PMC article.
The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice.
Bieghs V, Hendrikx T, van Gorp PJ, Verheyen F, Guichot YD, Walenbergh SM, Jeurissen ML, Gijbels M, Rensen SS, Bast A, Plat J, Kalhan SC, Koek GH, Leitersdorf E, Hofker MH, Lütjohann D, Shiri-Sverdlov R. Bieghs V, et al. Gastroenterology. 2013 Jan;144(1):167-178.e1. doi: 10.1053/j.gastro.2012.09.062. Epub 2012 Oct 3. Gastroenterology. 2013. PMID: 23041327
Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice.
Bot M, Van Veldhoven PP, de Jager SC, Johnson J, Nijstad N, Van Santbrink PJ, Westra MM, Van Der Hoeven G, Gijbels MJ, Müller-Tidow C, Varga G, Tietge UJ, Kuiper J, Van Berkel TJ, Nofer JR, Bot I, Biessen EA. Bot M, et al. Among authors: gijbels mj. PLoS One. 2013 May 20;8(5):e63360. doi: 10.1371/journal.pone.0063360. Print 2013. PLoS One. 2013. PMID: 23700419 Free PMC article.
Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype.
Hanssen NM, Wouters K, Huijberts MS, Gijbels MJ, Sluimer JC, Scheijen JL, Heeneman S, Biessen EA, Daemen MJ, Brownlee M, de Kleijn DP, Stehouwer CD, Pasterkamp G, Schalkwijk CG. Hanssen NM, et al. Among authors: gijbels mj. Eur Heart J. 2014 May;35(17):1137-46. doi: 10.1093/eurheartj/eht402. Epub 2013 Oct 14. Eur Heart J. 2014. PMID: 24126878
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.
Hoeksema MA, Gijbels MJ, Van den Bossche J, van der Velden S, Sijm A, Neele AE, Seijkens T, Stöger JL, Meiler S, Boshuizen MC, Dallinga-Thie GM, Levels JH, Boon L, Mullican SE, Spann NJ, Cleutjens JP, Glass CK, Lazar MA, de Vries CJ, Biessen EA, Daemen MJ, Lutgens E, de Winther MP. Hoeksema MA, et al. Among authors: gijbels mj. EMBO Mol Med. 2014 Sep;6(9):1124-32. doi: 10.15252/emmm.201404170. EMBO Mol Med. 2014. PMID: 25007801 Free PMC article.
204 results