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Dissecting the Structural and Chemical Determinants of the "Open-to-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria.
Rodrigo-Unzueta A, Ghirardello M, Urresti S, Delso I, Giganti D, Anso I, Trastoy B, Comino N, Tersa M, D'Angelo C, Cifuente JO, Marina A, Liebau J, Mäler L, Chenal A, Albesa-Jové D, Merino P, Guerin ME. Rodrigo-Unzueta A, et al. Among authors: giganti d. Biochemistry. 2020 Aug 18;59(32):2934-2945. doi: 10.1021/acs.biochem.0c00376. Epub 2020 Aug 4. Biochemistry. 2020. PMID: 32786405
Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria: implications for catalysis.
Guerin ME, Schaeffer F, Chaffotte A, Gest P, Giganti D, Korduláková J, van der Woerd M, Jackson M, Alzari PM. Guerin ME, et al. Among authors: giganti d. J Biol Chem. 2009 Aug 7;284(32):21613-25. doi: 10.1074/jbc.M109.003947. Epub 2009 Jun 11. J Biol Chem. 2009. PMID: 19520856 Free PMC article.
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance.
Manina G, Bellinzoni M, Pasca MR, Neres J, Milano A, Ribeiro AL, Buroni S, Skovierová H, Dianišková P, Mikušová K, Marák J, Makarov V, Giganti D, Haouz A, Lucarelli AP, Degiacomi G, Piazza A, Chiarelli LR, De Rossi E, Salina E, Cole ST, Alzari PM, Riccardi G. Manina G, et al. Among authors: giganti d. Mol Microbiol. 2010 Sep;77(5):1172-85. doi: 10.1111/j.1365-2958.2010.07277.x. Mol Microbiol. 2010. PMID: 20624223 Free article.
The force-dependent mechanism of DnaK-mediated mechanical folding.
Perales-Calvo J, Giganti D, Stirnemann G, Garcia-Manyes S. Perales-Calvo J, et al. Among authors: giganti d. Sci Adv. 2018 Feb 9;4(2):eaaq0243. doi: 10.1126/sciadv.aaq0243. eCollection 2018 Feb. Sci Adv. 2018. PMID: 29487911 Free PMC article.
21 results