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Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival.
Rico E, Oliva C, Gutierrez KJ, Alzate JF, Genes CM, Moreno D, Casanova E, Gigante A, Pérez-Pérez MJ, Camarasa MJ, Clos J, Gago F, Jiménez-Ruiz A. Rico E, et al. Among authors: gigante a. PLoS One. 2014 Feb 26;9(2):e89526. doi: 10.1371/journal.pone.0089526. eCollection 2014. PLoS One. 2014. PMID: 24651293 Free PMC article.
Microwave-assisted synthesis of C-8 aryl and heteroaryl inosines and determination of their inhibitory activities against Plasmodium falciparum purine nucleoside phosphorylase.
Gigante A, Priego EM, Sánchez-Carrasco P, Ruiz-Pérez LM, Vande Voorde J, Camarasa MJ, Balzarini J, González-Pacanowska D, Pérez-Pérez MJ. Gigante A, et al. Eur J Med Chem. 2014 Jul 23;82:459-65. doi: 10.1016/j.ejmech.2014.05.073. Epub 2014 Jun 2. Eur J Med Chem. 2014. PMID: 24929343 Free article.
Approved drugs screening against the nsP1 capping enzyme of Venezuelan equine encephalitis virus using an immuno-based assay.
Ferreira-Ramos AS, Li C, Eydoux C, Contreras JM, Morice C, Quérat G, Gigante A, Pérez Pérez MJ, Jung ML, Canard B, Guillemot JC, Decroly E, Coutard B. Ferreira-Ramos AS, et al. Among authors: gigante a. Antiviral Res. 2019 Mar;163:59-69. doi: 10.1016/j.antiviral.2019.01.003. Epub 2019 Jan 11. Antiviral Res. 2019. PMID: 30639438
Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors.
Kovacikova K, Gorostiola González M, Jones R, Reguera J, Gigante A, Pérez-Pérez MJ, Pürstinger G, Moesslacher J, Langer T, Jeong LS, Delang L, Neyts J, Snijder EJ, van Westen GJP, van Hemert MJ. Kovacikova K, et al. Among authors: gigante a. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0256620. doi: 10.1128/AAC.02566-20. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33875421 Free PMC article.
The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection.
Delang L, Li C, Tas A, Quérat G, Albulescu IC, De Burghgraeve T, Guerrero NA, Gigante A, Piorkowski G, Decroly E, Jochmans D, Canard B, Snijder EJ, Pérez-Pérez MJ, van Hemert MJ, Coutard B, Leyssen P, Neyts J. Delang L, et al. Among authors: gigante a. Sci Rep. 2016 Aug 22;6:31819. doi: 10.1038/srep31819. Sci Rep. 2016. PMID: 27545976 Free PMC article.
503 results