Gierut JJ - Search Results

1

Tissue-Specific Oncogenic Activity of KRAS^A146T.

Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM. Poulin EJ, et al. Among authors: gierut jj. Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5. Cancer Discov. 2019. PMID: 30952657 Free PMC article.

2

Oncogenic K-Ras promotes proliferation in quiescent intestinal stem cells.

Gierut JJ, Lyons J, Shah MS, Genetti C, Breault DT, Haigis KM. Gierut JJ, et al. Stem Cell Res. 2015 Jul;15(1):165-71. doi: 10.1016/j.scr.2015.06.003. Epub 2015 Jun 10. Stem Cell Res. 2015. PMID: 26079371 Free PMC article.

3

Network-level effects of kinase inhibitors modulate TNF-α-induced apoptosis in the intestinal epithelium.

Gierut JJ, Wood LB, Lau KS, Lin YJ, Genetti C, Samatar AA, Lauffenburger DA, Haigis KM. Gierut JJ, et al. Sci Signal. 2015 Dec 15;8(407):ra129. doi: 10.1126/scisignal.aac7235. Sci Signal. 2015. PMID: 26671150 Free PMC article.

4

Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.

Wang Y, Velho S, Vakiani E, Peng S, Bass AJ, Chu GC, Gierut J, Bugni JM, Der CJ, Philips M, Solit DB, Haigis KM. Wang Y, et al. Cancer Discov. 2013 Mar;3(3):294-307. doi: 10.1158/2159-8290.CD-12-0198. Epub 2012 Dec 28. Cancer Discov. 2013. PMID: 23274911 Free PMC article.

5

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α.

Lau KS, Schrier SB, Gierut J, Lyons J, Lauffenburger DA, Haigis KM. Lau KS, et al. Integr Biol (Camb). 2013 Nov;5(11):1355-65. doi: 10.1039/c3ib40062j. Epub 2013 Oct 2. Integr Biol (Camb). 2013. PMID: 24084984 Free PMC article.

6

Strategies to achieve conditional gene mutation in mice.

Gierut JJ, Jacks TE, Haigis KM. Gierut JJ, et al. Cold Spring Harb Protoc. 2014 Apr 1;2014(4):339-49. doi: 10.1101/pdb.top069807. Cold Spring Harb Protoc. 2014. PMID: 24692485 Free PMC article. Review.

7

The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile.

Lyons J, Ghazi PC, Starchenko A, Tovaglieri A, Baldwin KR, Poulin EJ, Gierut JJ, Genetti C, Yajnik V, Breault DT, Lauffenburger DA, Haigis KM. Lyons J, et al. Among authors: gierut jj. PLoS Biol. 2018 Mar 29;16(3):e2002417. doi: 10.1371/journal.pbio.2002417. eCollection 2018 Mar. PLoS Biol. 2018. PMID: 29596476 Free PMC article.

8

Producing and concentrating lenti-Cre for mouse infections.

Gierut JJ, Jacks TE, Haigis KM. Gierut JJ, et al. Cold Spring Harb Protoc. 2014 Mar 1;2014(3):304-6. doi: 10.1101/pdb.prot073437. Cold Spring Harb Protoc. 2014. PMID: 24591688 Free PMC article.

9

In vivo delivery of lenti-Cre or adeno-Cre into mice using intranasal instillation.

Gierut JJ, Jacks TE, Haigis KM. Gierut JJ, et al. Cold Spring Harb Protoc. 2014 Mar 1;2014(3):307-9. doi: 10.1101/pdb.prot073445. Cold Spring Harb Protoc. 2014. PMID: 24591689 Free PMC article.

10

Whole-mount X-Gal staining of mouse tissues.

Gierut JJ, Jacks TE, Haigis KM. Gierut JJ, et al. Cold Spring Harb Protoc. 2014 Apr 1;2014(4):417-9. doi: 10.1101/pdb.prot073452. Cold Spring Harb Protoc. 2014. PMID: 24692489 Free PMC article.

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