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Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome.
Campadelli-Fiume G, Collins-McMillen D, Gianni T, Yurochko AD. Campadelli-Fiume G, et al. Among authors: gianni t. Annu Rev Virol. 2016 Sep 29;3(1):215-236. doi: 10.1146/annurev-virology-110615-035618. Epub 2016 Aug 3. Annu Rev Virol. 2016. PMID: 27501260 Review.
A heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion.
Gianni T, Menotti L, Campadelli-Fiume G. Gianni T, et al. J Virol. 2005 Jun;79(11):7042-9. doi: 10.1128/JVI.79.11.7042-7049.2005. J Virol. 2005. PMID: 15890943 Free PMC article.
Recently, we reported that the ectodomain of HSV-1 gH carries a hydrophobic alpha-helix (residues 377 to 397) with attributes of an internal fusion peptide (T. Gianni, P. L. Martelli, R. Casadio, and G. Campadelli-Fiume, J. ...
Recently, we reported that the ectodomain of HSV-1 gH carries a hydrophobic alpha-helix (residues 377 to 397) with attributes of an internal …
Hydrophobic alpha-helices 1 and 2 of herpes simplex virus gH interact with lipids, and their mimetic peptides enhance virus infection and fusion.
Gianni T, Fato R, Bergamini C, Lenaz G, Campadelli-Fiume G. Gianni T, et al. J Virol. 2006 Aug;80(16):8190-8. doi: 10.1128/JVI.00504-06. J Virol. 2006. PMID: 16873275 Free PMC article.
This contrasts with alpha-H1, which cannot be deleted and can be functionally replaced with heterologous fusion peptides (T. Gianni et al., J. Virol. 79:2931-2940, 2005). Synthetic peptides mimicking alpha-H1 and alpha-H2 induced fusion of nude lipid vesicles. ...
This contrasts with alpha-H1, which cannot be deleted and can be functionally replaced with heterologous fusion peptides (T. Giann
45 results