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Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas.
Kuburich NA, den Hollander P, Castaneda M, Pietilä M, Tang X, Batra H, Martínez-Peña F, Visal TH, Zhou T, Demestichas BR, Dontula RV, Liu JY, Maddela JJ, Padmanabhan RS, Phi LTH, Rosolen MJ, Sabapathy T, Kumar D, Giancotti FG, Lairson LL, Raso MG, Soundararajan R, Mani SA. Kuburich NA, et al. Among authors: giancotti fg. Cell Rep. 2023 Dec 26;42(12):113470. doi: 10.1016/j.celrep.2023.113470. Epub 2023 Nov 20. Cell Rep. 2023. PMID: 37979166 Free PMC article.
Metastatic colorectal cancer: mechanisms and emerging therapeutics.
Shin AE, Giancotti FG, Rustgi AK. Shin AE, et al. Among authors: giancotti fg. Trends Pharmacol Sci. 2023 Apr;44(4):222-236. doi: 10.1016/j.tips.2023.01.003. Epub 2023 Feb 23. Trends Pharmacol Sci. 2023. PMID: 36828759 Free PMC article. Review.
STAT3 protects hematopoietic stem cells by preventing activation of a deleterious autocrine type-I interferon response.
Patel B, Zhou Y, Babcock RL, Ma F, Zal MA, Kumar D, Medik YB, Kahn LM, Pineda JE, Park EM, Schneider SM, Tang X, Raso MG, Jeter CR, Zal T, Clise-Dwyer K, Keyomarsi K, Giancotti FG, Colla S, Watowich SS. Patel B, et al. Among authors: giancotti fg. Leukemia. 2024 May;38(5):1143-1155. doi: 10.1038/s41375-024-02218-6. Epub 2024 Mar 11. Leukemia. 2024. PMID: 38467768
The Hippo pathway mediates Semaphorin signaling.
Meng Z, Li FL, Fang C, Yeoman B, Qiu Y, Wang Y, Cai X, Lin KC, Yang D, Luo M, Fu V, Ma X, Diao Y, Giancotti FG, Ren B, Engler AJ, Guan KL. Meng Z, et al. Among authors: giancotti fg. Sci Adv. 2022 May 27;8(21):eabl9806. doi: 10.1126/sciadv.abl9806. Epub 2022 May 25. Sci Adv. 2022. PMID: 35613278 Free PMC article.
Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis.
Han H, Wang Y, Curto J, Gurrapu S, Laudato S, Rumandla A, Chakraborty G, Wang X, Chen H, Jiang Y, Kumar D, Caggiano EG, Capogiri M, Zhang B, Ji Y, Maity SN, Hu M, Bai S, Aparicio AM, Efstathiou E, Logothetis CJ, Navin N, Navone NM, Chen Y, Giancotti FG. Han H, et al. Among authors: giancotti fg. Cell Rep. 2022 Apr 5;39(1):110595. doi: 10.1016/j.celrep.2022.110595. Cell Rep. 2022. PMID: 35385726 Free PMC article.
Phase 0 Clinical Trial of Everolimus in Patients with Vestibular Schwannoma or Meningioma.
Karajannis MA, Mauguen A, Maloku E, Xu Q, Dunbar EM, Plotkin SR, Yaffee A, Wang S, Roland JT, Sen C, Placantonakis DG, Golfinos JG, Allen JC, Vitanza NA, Chiriboga LA, Schneider RJ, Deng J, Neubert TA, Goldberg JD, Zagzag D, Giancotti FG, Blakeley JO. Karajannis MA, et al. Among authors: giancotti fg. Mol Cancer Ther. 2021 Sep;20(9):1584-1591. doi: 10.1158/1535-7163.MCT-21-0143. Epub 2021 Jun 17. Mol Cancer Ther. 2021. PMID: 34224367 Free PMC article.
Prostate epithelial genes define therapy-relevant prostate cancer molecular subtype.
Han H, Lee HH, Choi K, Moon YJ, Heo JE, Ham WS, Jang WS, Rha KH, Cho NH, Giancotti FG, Choi YD. Han H, et al. Among authors: giancotti fg. Prostate Cancer Prostatic Dis. 2021 Dec;24(4):1080-1092. doi: 10.1038/s41391-021-00364-x. Epub 2021 Apr 26. Prostate Cancer Prostatic Dis. 2021. PMID: 33903734 Free PMC article.
109 results