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Scientific considerations for global drug development.
Wilson JL, Cheung KWK, Lin L, Green EAE, Porrás AI, Zou L, Mukanga D, Akpa PA, Darko DM, Yuan R, Ding S, Johnson WCN, Lee HA, Cooke E, Peck CC, Kern SE, Hartman D, Hayashi Y, Marks PW, Altman RB, Lumpkin MM, Giacomini KM, Blaschke TF. Wilson JL, et al. Among authors: giacomini km. Sci Transl Med. 2020 Jul 29;12(554):eaax2550. doi: 10.1126/scitranslmed.aax2550. Sci Transl Med. 2020. PMID: 32727913 Free PMC article. Review.
Stereoselective binding of disopyramide to plasma proteins.
Valdivieso L, Giacomini KM, Nelson WL, Pershe R, Blaschke TF. Valdivieso L, et al. Among authors: giacomini km. Pharm Res. 1988 May;5(5):316-8. doi: 10.1023/a:1015986906627. Pharm Res. 1988. PMID: 3244643 No abstract available.
The pharmacogenetics research network: from SNP discovery to clinical drug response.
Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I; Pharmacogenetics Research Network. Giacomini KM, et al. Clin Pharmacol Ther. 2007 Mar;81(3):328-45. doi: 10.1038/sj.clpt.6100087. Clin Pharmacol Ther. 2007. PMID: 17339863 Free PMC article. Review.
SLC19A1 pharmacogenomics summary.
Yee SW, Gong L, Badagnani I, Giacomini KM, Klein TE, Altman RB. Yee SW, et al. Among authors: giacomini km. Pharmacogenet Genomics. 2010 Nov;20(11):708-15. doi: 10.1097/FPC.0b013e32833eca92. Pharmacogenet Genomics. 2010. PMID: 20811316 Free PMC article. No abstract available.
Metformin pathways: pharmacokinetics and pharmacodynamics.
Gong L, Goswami S, Giacomini KM, Altman RB, Klein TE. Gong L, et al. Among authors: giacomini km. Pharmacogenet Genomics. 2012 Nov;22(11):820-7. doi: 10.1097/FPC.0b013e3283559b22. Pharmacogenet Genomics. 2012. PMID: 22722338 Free PMC article. Review. No abstract available.
SLC transporters as therapeutic targets: emerging opportunities.
Lin L, Yee SW, Kim RB, Giacomini KM. Lin L, et al. Among authors: giacomini km. Nat Rev Drug Discov. 2015 Aug;14(8):543-60. doi: 10.1038/nrd4626. Epub 2015 Jun 26. Nat Rev Drug Discov. 2015. PMID: 26111766 Free PMC article. Review.
346 results