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Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood.
Tata B, Mimouni NEH, Barbotin AL, Malone SA, Loyens A, Pigny P, Dewailly D, Catteau-Jonard S, Sundström-Poromaa I, Piltonen TT, Dal Bello F, Medana C, Prevot V, Clasadonte J, Giacobini P. Tata B, et al. Among authors: giacobini p. Nat Med. 2018 Jun;24(6):834-846. doi: 10.1038/s41591-018-0035-5. Epub 2018 May 14. Nat Med. 2018. PMID: 29760445 Free PMC article.
Pregnancy and neonatal complications in women with polycystic ovary syndrome in relation to second-trimester anti-Müllerian hormone levels.
Valdimarsdottir R, Valgeirsdottir H, Wikström AK, Kallak TK, Elenis E, Axelsson O, Ubhayasekhera K, Bergquist J, Piltonen TT, Pigny P, Giacobini P, Poromaa IS. Valdimarsdottir R, et al. Among authors: giacobini p. Reprod Biomed Online. 2019 Jul;39(1):141-148. doi: 10.1016/j.rbmo.2019.02.004. Epub 2019 Feb 27. Reprod Biomed Online. 2019. PMID: 31036431
Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process.
Mimouni NEH, Paiva I, Barbotin AL, Timzoura FE, Plassard D, Le Gras S, Ternier G, Pigny P, Catteau-Jonard S, Simon V, Prevot V, Boutillier AL, Giacobini P. Mimouni NEH, et al. Among authors: giacobini p. Cell Metab. 2021 Mar 2;33(3):513-530.e8. doi: 10.1016/j.cmet.2021.01.004. Epub 2021 Feb 3. Cell Metab. 2021. PMID: 33539777 Free PMC article.
82 results