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Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino GI, Palluzzi F, Chiariello AM, Piccioni R, Bianco S, Furia L, De Conti G, Bouwman BAM, Melloni G, Guido D, Giacò L, Luzi L, Cittaro D, Faretta M, Nicodemi M, Crosetto N, Pelicci PG. Dellino GI, et al. Among authors: giaco l. Nat Genet. 2019 Jun;51(6):1011-1023. doi: 10.1038/s41588-019-0421-z. Epub 2019 May 20. Nat Genet. 2019. PMID: 31110352
The impact of the COVID-19 pandemic on oncological disease extent at FDG PET/CT staging: the ONCOVIPET study.
Caldarella C, Cocciolillo F, Taralli S, Lorusso M, Scolozzi V, Pizzuto DA, Calcagni ML, Rufini V, Guido D, Palluzzi F, Giacò L, Giordano A, Leccisotti L. Caldarella C, et al. Among authors: giaco l. Eur J Nucl Med Mol Imaging. 2022 Apr;49(5):1623-1629. doi: 10.1007/s00259-021-05629-0. Epub 2021 Dec 8. Eur J Nucl Med Mol Imaging. 2022. PMID: 34877609 Free PMC article.
Identification of a novel gene signature predicting response to first-line chemotherapy in BRCA wild-type high-grade serous ovarian cancer patients.
Buttarelli M, Ciucci A, Palluzzi F, Raspaglio G, Marchetti C, Perrone E, Minucci A, Giacò L, Fagotti A, Scambia G, Gallo D. Buttarelli M, et al. Among authors: giaco l. J Exp Clin Cancer Res. 2022 Feb 4;41(1):50. doi: 10.1186/s13046-022-02265-w. J Exp Clin Cancer Res. 2022. PMID: 35120576 Free PMC article.
BORN study: a multicenter randomized trial investigating cord blood red blood cell transfusions to reduce the severity of retinopathy of prematurity in extremely low gestational age neonates.
Teofili L, Papacci P, Orlando N, Bianchi M, Pasciuto T, Mozzetta I, Palluzzi F, Giacò L, Giannantonio C, Remaschi G, Santosuosso M, Beccastrini E, Fabbri M, Valentini CG, Bonfini T, Cloclite E, Accorsi P, Dragonetti A, Cresi F, Ansaldi G, Raffaeli G, Villa S, Pucci G, Mondello I, Santodirocco M, Ghirardello S, Vento G. Teofili L, et al. Among authors: giaco l. Trials. 2022 Dec 13;23(1):1010. doi: 10.1186/s13063-022-06949-8. Trials. 2022. PMID: 36514106 Free PMC article. Clinical Trial.
A Computational Framework for Comprehensive Genomic Profiling in Solid Cancers: The Analytical Performance of a High-Throughput Assay for Small and Copy Number Variants.
Giacò L, Palluzzi F, Guido D, Nero C, Giacomini F, Duranti S, Bria E, Tortora G, Cenci T, Martini M, De Paolis E, Onori ME, De Bonis M, Normanno N, Scambia G, Minucci A. Giacò L, et al. Cancers (Basel). 2022 Dec 13;14(24):6152. doi: 10.3390/cancers14246152. Cancers (Basel). 2022. PMID: 36551638 Free PMC article.
Evaluating the Risk of Inguinal Lymph Node Metastases before Surgery Using the Morphonode Predictive Model: A Prospective Diagnostic Study in Vulvar Cancer Patients.
Fragomeni SM, Moro F, Palluzzi F, Mascilini F, Rufini V, Collarino A, Inzani F, Giacò L, Scambia G, Testa AC, Garganese G. Fragomeni SM, et al. Among authors: giaco l. Cancers (Basel). 2023 Feb 9;15(4):1121. doi: 10.3390/cancers15041121. Cancers (Basel). 2023. PMID: 36831462 Free PMC article.
Unexpected finding of a rare pathogenic germline BRCA1 variant in an intrahepatic cholangiocarcinoma using the Oncomine Focus DNA assay: clinical and diagnostic implications.
De Bonis M, Mannavola F, Salvatore L, De Paolis E, Nero C, Giacò L, Tortora G, Giuliante F, Urbani A, Scambia G, Normanno N, Minucci A. De Bonis M, et al. Among authors: giaco l. Mol Biol Rep. 2023 Aug;50(8):7113-7120. doi: 10.1007/s11033-023-08588-x. Epub 2023 Jun 20. Mol Biol Rep. 2023. PMID: 37340184
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