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Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction.
Bum-Erdene K, Zhou D, Gonzalez-Gutierrez G, Ghozayel MK, Si Y, Xu D, Shannon HE, Bailey BJ, Corson TW, Pollok KE, Wells CD, Meroueh SO. Bum-Erdene K, et al. Among authors: ghozayel mk. Cell Chem Biol. 2019 Mar 21;26(3):378-389.e13. doi: 10.1016/j.chembiol.2018.11.010. Epub 2018 Dec 20. Cell Chem Biol. 2019. PMID: 30581134 Free article.
Small-Molecule Cyanamide Pan-TEAD·YAP1 Covalent Antagonists.
Bum-Erdene K, Yeh IJ, Gonzalez-Gutierrez G, Ghozayel MK, Pollok K, Meroueh SO. Bum-Erdene K, et al. Among authors: ghozayel mk. J Med Chem. 2023 Jan 12;66(1):266-284. doi: 10.1021/acs.jmedchem.2c01189. Epub 2022 Dec 23. J Med Chem. 2023. PMID: 36562717
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