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Page 1
RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition.
Nunes C, Depestel L, Mus L, Keller KM, Delhaye L, Louwagie A, Rishfi M, Whale A, Kara N, Andrews SR, Dela Cruz F, You D, Siddiquee A, Cologna CT, De Craemer S, Dolman E, Bartenhagen C, De Vloed F, Sanders E, Eggermont A, Bekaert SL, Van Loocke W, Bek JW, Dewyn G, Loontiens S, Van Isterdael G, Decaesteker B, Tilleman L, Van Nieuwerburgh F, Vermeirssen V, Van Neste C, Ghesquiere B, Goossens S, Eyckerman S, De Preter K, Fischer M, Houseley J, Molenaar J, De Wilde B, Roberts SS, Durinck K, Speleman F. Nunes C, et al. Among authors: ghesquiere b. Sci Adv. 2022 Jul 15;8(28):eabn1382. doi: 10.1126/sciadv.abn1382. Epub 2022 Jul 13. Sci Adv. 2022. PMID: 35857500 Free PMC article.
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease.
Ryan EM, Sadiku P, Coelho P, Watts ER, Zhang A, Howden AJM, Sanchez-Garcia MA, Bewley M, Cole J, McHugh BJ, Vermaelen W, Ghesquiere B, Carmeliet P, Rodriguez Blanco G, Von Kriegsheim A, Sanchez Y, Rumsey W, Callahan JF, Cooper G, Parkinson N, Baillie K, Cantrell DA, McCafferty J, Choudhury G, Singh D, Dockrell DH, Whyte MKB, Walmsley SR. Ryan EM, et al. Among authors: ghesquiere b. Am J Respir Crit Care Med. 2023 Apr 15;207(8):998-1011. doi: 10.1164/rccm.202203-0482OC. Am J Respir Crit Care Med. 2023. PMID: 36724365 Free PMC article.
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.
Roels J, Thénoz M, Szarzyńska B, Landfors M, De Coninck S, Demoen L, Provez L, Kuchmiy A, Strubbe S, Reunes L, Pieters T, Matthijssens F, Van Loocke W, Erarslan-Uysal B, Richter-Pechańska P, Declerck K, Lammens T, De Moerloose B, Deforce D, Van Nieuwerburgh F, Cheung LC, Kotecha RS, Mansour MR, Ghesquière B, Van Camp G, Berghe WV, Kowalczyk JR, Szczepański T, Davé UP, Kulozik AE, Goossens S, Curtis DJ, Taghon T, Dawidowska M, Degerman S, Van Vlierberghe P. Roels J, et al. Among authors: ghesquiere b. Blood Cancer Discov. 2020 Nov;1(3):274-289. doi: 10.1158/2643-3230.BCD-20-0059. Epub 2020 Sep 23. Blood Cancer Discov. 2020. PMID: 33179015 Free PMC article.
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma.
Mestdagh P, Boström AK, Impens F, Fredlund E, Van Peer G, De Antonellis P, von Stedingk K, Ghesquière B, Schulte S, Dews M, Thomas-Tikhonenko A, Schulte JH, Zollo M, Schramm A, Gevaert K, Axelson H, Speleman F, Vandesompele J. Mestdagh P, et al. Among authors: ghesquiere b. Mol Cell. 2010 Dec 10;40(5):762-73. doi: 10.1016/j.molcel.2010.11.038. Mol Cell. 2010. PMID: 21145484 Free PMC article.
Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells.
Kerselidou D, Dohai BS, Nelson DR, Daakour S, De Cock N, Hassoun ZAO, Kim DK, Olivet J, El Assal DC, Jaiswal A, Alzahmi A, Saha D, Pain C, Matthijssens F, Lemaitre P, Herfs M, Chapuis J, Ghesquiere B, Vertommen D, Kriechbaumer V, Knoops K, Lopez-Iglesias C, van Zandvoort M, Lambert JC, Hanson J, Desmet C, Thiry M, Lauersen KJ, Vidal M, Van Vlierberghe P, Dequiedt F, Salehi-Ashtiani K, Twizere JC. Kerselidou D, et al. Among authors: ghesquiere b. Sci Adv. 2021 May 7;7(19):eabe8349. doi: 10.1126/sciadv.abe8349. Print 2021 May. Sci Adv. 2021. PMID: 33962942 Free PMC article.
Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation.
Virga F, Cappellesso F, Stijlemans B, Henze AT, Trotta R, Van Audenaerde J, Mirchandani AS, Sanchez-Garcia MA, Vandewalle J, Orso F, Riera-Domingo C, Griffa A, Ivan C, Smits E, Laoui D, Martelli F, Langouche L, Van den Berghe G, Feron O, Ghesquière B, Prenen H, Libert C, Walmsley SR, Corbet C, Van Ginderachter JA, Ivan M, Taverna D, Mazzone M. Virga F, et al. Among authors: ghesquiere b. Sci Adv. 2021 May 7;7(19):eabf0466. doi: 10.1126/sciadv.abf0466. Print 2021 May. Sci Adv. 2021. PMID: 33962944 Free article.
How tech-savvy employees make the difference in core facilities: Recognizing core facility expertise with dedicated career tracks: Recognizing core facility expertise with dedicated career tracks.
Lippens S, Audenaert D, Botzki A, Derveaux S, Ghesquière B, Goeminne G, Hassanzadeh R, Haustraete J, Impens F, Lamote J, Munck S, Vandamme N, Van Isterdael G, Lein M, Van Minnebruggen G. Lippens S, et al. Among authors: ghesquiere b. EMBO Rep. 2022 Jun 7;23(6):e55094. doi: 10.15252/embr.202255094. Epub 2022 Jun 1. EMBO Rep. 2022. PMID: 35652151 Free PMC article.
Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer.
Van den Broeck T, Moris L, Gevaert T, Davicioni E, Boeckx B, Lambrechts D, Helsen C, Handle F, Ghesquière B, Soenen S, Smeets E, Eerlings R, El Kharraz S, Devlies W, Karnes RJ, Lotan T, Van Poppel H, Joniau S, Claessens F. Van den Broeck T, et al. Among authors: ghesquiere b. Mol Cancer Res. 2022 Apr 1;20(4):527-541. doi: 10.1158/1541-7786.MCR-21-0388. Mol Cancer Res. 2022. PMID: 35082164
Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis.
Oudaert I, Satilmis H, Vlummens P, De Brouwer W, Maes A, Hose D, De Bruyne E, Ghesquière B, Vanderkerken K, De Veirman K, Menu E. Oudaert I, et al. Among authors: ghesquiere b. J Exp Clin Cancer Res. 2022 Feb 1;41(1):45. doi: 10.1186/s13046-022-02250-3. J Exp Clin Cancer Res. 2022. PMID: 35105345 Free PMC article.
129 results