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Page 1
Glycosphingolipids in congenital disorders of glycosylation (CDG).
Jáñez Pedrayes A, Rymen D, Ghesquière B, Witters P. Jáñez Pedrayes A, et al. Among authors: ghesquiere b. Mol Genet Metab. 2024 May;142(1):108434. doi: 10.1016/j.ymgme.2024.108434. Epub 2024 Mar 5. Mol Genet Metab. 2024. PMID: 38489976 Review.
Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models.
Radenkovic S, Budhraja R, Klein-Gunnewiek T, King AT, Bhatia TN, Ligezka AN, Driesen K, Shah R, Ghesquière B, Pandey A, Kasri NN, Sloan SA, Morava E, Kozicz T. Radenkovic S, et al. Among authors: ghesquiere b. Cell Rep. 2024 Mar 26;43(3):113883. doi: 10.1016/j.celrep.2024.113883. Epub 2024 Mar 1. Cell Rep. 2024. PMID: 38430517 Free article.
Ancient genomic linkage couples metabolism with erythroid development.
Preston AE, Frost JN, Badat M, Teh M, Armitage AE, Norfo R, Wideman SK, Hanifi M, White N, Roy N, Ghesquiere B, Babbs C, Kassouf M, Davies J, Hughes JR, Beagrie R, Higgs DR, Drakesmith H. Preston AE, et al. Among authors: ghesquiere b. bioRxiv [Preprint]. 2023 Sep 25:2023.09.25.558944. doi: 10.1101/2023.09.25.558944. bioRxiv. 2023. PMID: 37808769 Free PMC article. Preprint.
Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells.
Sneyers F, Kerkhofs M, Speelman-Rooms F, Welkenhuyzen K, La Rovere R, Shemy A, Voet A, Eelen G, Dewerchin M, Tait SWG, Ghesquière B, Bootman MD, Bultynck G. Sneyers F, et al. Among authors: ghesquiere b. Cell Death Dis. 2023 Sep 8;14(9):600. doi: 10.1038/s41419-023-06120-4. Cell Death Dis. 2023. PMID: 37684238 Free PMC article.
13C tracer analysis reveals the landscape of metabolic checkpoints in human CD8+ T cell differentiation and exhaustion.
Kirchmair A, Nemati N, Lamberti G, Trefny M, Krogsdam A, Siller A, Hörtnagl P, Schumacher P, Sopper S, Sandbichler A, Zippelius A, Ghesquière B, Trajanoski Z. Kirchmair A, et al. Among authors: ghesquiere b. Front Immunol. 2023 Oct 19;14:1267816. doi: 10.3389/fimmu.2023.1267816. eCollection 2023. Front Immunol. 2023. PMID: 37928527 Free PMC article.
Glucocorticoid dysfunction in children with severe malaria.
Vandermosten L, Prenen F, Fogang B, Dagneau de Richecour P, Knoops S, Donkeu CJ, Nguefack CDP, Taguebue JV, Ndombo PK, Ghesquière B, Ayong L, Van den Steen PE. Vandermosten L, et al. Among authors: ghesquiere b. Front Immunol. 2023 Jul 10;14:1187196. doi: 10.3389/fimmu.2023.1187196. eCollection 2023. Front Immunol. 2023. PMID: 37492570 Free PMC article.
Mitochondrial adaptation decreases drug sensitivity of persistent triple negative breast cancer cells surviving combinatory and sequential chemotherapy.
Winter M, Nait Eldjoudi A, Guette C, Hondermarck H, Bourette RP, Fovez Q, Laine W, Ghesquiere B, Adriaenssens E, Kluza J, Le Bourhis X. Winter M, et al. Among authors: ghesquiere b. Neoplasia. 2023 Dec;46:100949. doi: 10.1016/j.neo.2023.100949. Epub 2023 Nov 11. Neoplasia. 2023. PMID: 37956532 Free PMC article.
ACSM1 and ACSM3 regulate fatty acid metabolism to support prostate cancer growth and constrain ferroptosis.
Shrestha RK, Nassar ZD, Hanson AR, Iggo R, Townley SL, Dehairs J, Mah CY, Helm M, Alizadeh-Ghodsi M, Pickering M, Ghesquiere B, Watt MJ, Quek LE, Hoy AJ, Tilley WD, Swinnen JV, Butler LM, Selth LA. Shrestha RK, et al. Among authors: ghesquiere b. Cancer Res. 2024 Apr 24. doi: 10.1158/0008-5472.CAN-23-1489. Online ahead of print. Cancer Res. 2024. PMID: 38657108
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming.
Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, Kobold S, Kastenmüller W, Vaeth M. Wu H, et al. Among authors: ghesquiere b. Nat Commun. 2023 Oct 27;14(1):6858. doi: 10.1038/s41467-023-42634-3. Nat Commun. 2023. PMID: 37891230 Free PMC article.
129 results