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Tissue-Specific Oncogenic Activity of KRASA146T.
Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5.
Cancer Discov. 2019.
PMID: 30952657
Free PMC article.
Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis.
Lyons J, Brubaker DK, Ghazi PC, Baldwin KR, Edwards A, Boukhali M, Strasser SD, Suarez-Lopez L, Lin YJ, Yajnik V, Kissil JL, Haas W, Lauffenburger DA, Haigis KM.
Lyons J, et al. Among authors: ghazi pc.
Sci Signal. 2018 Feb 27;11(519):eaan3580. doi: 10.1126/scisignal.aan3580.
Sci Signal. 2018.
PMID: 29487189
Free PMC article.
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Substrate-based kinase activity inference identifies MK2 as driver of colitis.
Strasser SD, Ghazi PC, Starchenko A, Boukhali M, Edwards A, Suarez-Lopez L, Lyons J, Changelian PS, Monahan JB, Jacobsen J, Brubaker DK, Joughin BA, Yaffe MB, Haas W, Lauffenburger DA, Haigis KM.
Strasser SD, et al. Among authors: ghazi pc.
Integr Biol (Camb). 2019 Nov 26;11(7):301-314. doi: 10.1093/intbio/zyz025.
Integr Biol (Camb). 2019.
PMID: 31617572
Free PMC article.
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The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile.
Lyons J, Ghazi PC, Starchenko A, Tovaglieri A, Baldwin KR, Poulin EJ, Gierut JJ, Genetti C, Yajnik V, Breault DT, Lauffenburger DA, Haigis KM.
Lyons J, et al. Among authors: ghazi pc.
PLoS Biol. 2018 Mar 29;16(3):e2002417. doi: 10.1371/journal.pbio.2002417. eCollection 2018 Mar.
PLoS Biol. 2018.
PMID: 29596476
Free PMC article.
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Chloroquine Sensitizes GNAQ/11-mutated Melanoma to MEK1/2 Inhibition.
Truong A, Yoo JH, Scherzer MT, Sanchez JMS, Dale KJ, Kinsey CG, Richards JR, Shin D, Ghazi PC, Onken MD, Blumer KJ, Odelberg SJ, McMahon M.
Truong A, et al. Among authors: ghazi pc.
Clin Cancer Res. 2020 Dec 1;26(23):6374-6386. doi: 10.1158/1078-0432.CCR-20-1675. Epub 2020 Sep 15.
Clin Cancer Res. 2020.
PMID: 32933997
Free PMC article.
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Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer.
Vaishnavi A, Scherzer MT, Kinsey CG, Parkman GL, Truong A, Ghazi P, Schuman S, Battistone B, Garrido-Laguna I, McMahon M.
Vaishnavi A, et al.
Cell Rep. 2020 Aug 4;32(5):107994. doi: 10.1016/j.celrep.2020.107994.
Cell Rep. 2020.
PMID: 32755586
Free PMC article.
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Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer.
Ghazi PC, O'Toole KT, Srinivas Boggaram S, Scherzer MT, Silvis MR, Zhang Y, Bogdan M, Smith BD, Lozano G, Flynn DL, Snyder EL, Kinsey CG, McMahon M.
Ghazi PC, et al.
bioRxiv [Preprint]. 2024 Feb 8:2024.02.06.579200. doi: 10.1101/2024.02.06.579200.
bioRxiv. 2024.
PMID: 38370808
Free PMC article.
Preprint.
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Simultaneous cytosolic delivery of a chemotherapeutic and siRNA using nanoparticle-stabilized nanocapsules.
Hardie J, Jiang Y, Tetrault ER, Ghazi PC, Tonga GY, Farkas ME, Rotello VM.
Hardie J, et al. Among authors: ghazi pc.
Nanotechnology. 2016 Sep 16;27(37):374001. doi: 10.1088/0957-4484/27/37/374001. Epub 2016 Aug 9.
Nanotechnology. 2016.
PMID: 27505356
Free PMC article.
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