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3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae.
Verma A, Wong DM, Islam R, Tong F, Ghavami M, Mutunga JM, Slebodnick C, Li J, Viayna E, Lam PC, Totrov MM, Bloomquist JR, Carlier PR. Verma A, et al. Among authors: ghavami m. Bioorg Med Chem. 2015 Mar 15;23(6):1321-40. doi: 10.1016/j.bmc.2015.01.026. Epub 2015 Jan 22. Bioorg Med Chem. 2015. PMID: 25684426 Free PMC article.
Biological Studies and Target Engagement of the 2- C-Methyl-d-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1 R,3 S)-MMV008138 and Analogs.
Ghavami M, Merino EF, Yao ZK, Elahi R, Simpson ME, Fernández-Murga ML, Butler JH, Casasanta MA, Krai PM, Totrov MM, Slade DJ, Carlier PR, Cassera MB. Ghavami M, et al. ACS Infect Dis. 2018 Apr 13;4(4):549-559. doi: 10.1021/acsinfecdis.7b00159. Epub 2017 Nov 7. ACS Infect Dis. 2018. PMID: 29072835 Free PMC article.
111 results