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Page 1
A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.
Seldin MM, Koplev S, Rajbhandari P, Vergnes L, Rosenberg GM, Meng Y, Pan C, Phuong TMN, Gharakhanian R, Che N, Mäkinen S, Shih DM, Civelek M, Parks BW, Kim ED, Norheim F, Chella Krishnan K, Hasin-Brumshtein Y, Mehrabian M, Laakso M, Drevon CA, Koistinen HA, Tontonoz P, Reue K, Cantor RM, Björkegren JLM, Lusis AJ. Seldin MM, et al. Among authors: gharakhanian r. Cell Metab. 2018 May 1;27(5):1138-1155.e6. doi: 10.1016/j.cmet.2018.03.015. Cell Metab. 2018. PMID: 29719227 Free PMC article.
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.
Shum M, Shintre CA, Althoff T, Gutierrez V, Segawa M, Saxberg AD, Martinez M, Adamson R, Young MR, Faust B, Gharakhanian R, Su S, Chella Krishnan K, Mahdaviani K, Veliova M, Wolf DM, Ngo J, Nocito L, Stiles L, Abramson J, Lusis AJ, Hevener AL, Zoghbi ME, Carpenter EP, Liesa M. Shum M, et al. Among authors: gharakhanian r. Sci Transl Med. 2021 May 19;13(594):eabd1869. doi: 10.1126/scitranslmed.abd1869. Sci Transl Med. 2021. PMID: 34011630 Free PMC article.
Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.
Shum M, Segawa M, Gharakhanian R, Viñuela A, Wortham M, Baghdasarian S, Wolf DM, Sereda SB, Nocito L, Stiles L, Zhou Z, Gutierrez V, Sander M, Shirihai OS, Liesa M. Shum M, et al. Among authors: gharakhanian r. Mol Metab. 2022 Jan;55:101403. doi: 10.1016/j.molmet.2021.101403. Epub 2021 Nov 23. Mol Metab. 2022. PMID: 34823065 Free PMC article.
Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.
Mahdaviani K, Benador IY, Su S, Gharakhanian RA, Stiles L, Trudeau KM, Cardamone M, Enríquez-Zarralanga V, Ritou E, Aprahamian T, Oliveira MF, Corkey BE, Perissi V, Liesa M, Shirihai OS. Mahdaviani K, et al. Among authors: gharakhanian ra. EMBO Rep. 2017 Jul;18(7):1123-1138. doi: 10.15252/embr.201643827. Epub 2017 May 24. EMBO Rep. 2017. PMID: 28539390 Free PMC article.
Valley fever, mimicker of malignancy.
Gharakhanian R, Ohno A, Craig D, Wang S. Gharakhanian R, et al. Heliyon. 2023 Jan 10;9(1):e12900. doi: 10.1016/j.heliyon.2023.e12900. eCollection 2023 Jan. Heliyon. 2023. PMID: 36685442 Free PMC article.