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Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
van Straalen KR, Ma F, Tsou PS, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. van Straalen KR, et al. Among authors: gharaee kermani m. J Clin Invest. 2024 Feb 1;134(3):e169225. doi: 10.1172/JCI169225. J Clin Invest. 2024. PMID: 38051587 Free PMC article.
The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.
Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE. Billi AC, et al. JCI Insight. 2019 Apr 18;4(8):e127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18. JCI Insight. 2019. PMID: 30996136 Free PMC article.
IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation.
Gharaee-Kermani M, Estadt SN, Tsoi LC, Wolf-Fortune SJ, Liu J, Xing X, Theros J, Reed TJ, Lowe L, Gruszka D, Ward NL, Gudjonsson JE, Kahlenberg JM. Gharaee-Kermani M, et al. J Invest Dermatol. 2022 Jan;142(1):155-165.e3. doi: 10.1016/j.jid.2021.05.029. Epub 2021 Aug 5. J Invest Dermatol. 2022. PMID: 34364883 Free PMC article.
Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation.
Billi AC, Ma F, Plazyo O, Gharaee-Kermani M, Wasikowski R, Hile GA, Xing X, Yee CM, Rizvi SM, Maz MP, Berthier CC, Wen F, Tsoi LC, Pellegrini M, Modlin RL, Gudjonsson JE, Kahlenberg JM. Billi AC, et al. Sci Transl Med. 2022 Apr 27;14(642):eabn2263. doi: 10.1126/scitranslmed.abn2263. Epub 2022 Apr 27. Sci Transl Med. 2022. PMID: 35476593 Free PMC article.
Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin.
Hile GA, Coit P, Xu B, Victory AM, Gharaee-Kermani M, Estadt SN, Maz MP, Martens JWS, Wasikowski R, Dobry C, Tsoi LC, Iglesias-Bartolome R, Berthier CC, Billi AC, Gudjonsson JE, Sawalha AH, Kahlenberg JM. Hile GA, et al. Arthritis Rheumatol. 2023 Jul;75(7):1216-1228. doi: 10.1002/art.42460. Epub 2023 Apr 18. Arthritis Rheumatol. 2023. PMID: 36704840
Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin.
Wiedemann J, Billi AC, Bocci F, Kashgari G, Xing E, Tsoi LC, Meller L, Swindell WR, Wasikowski R, Xing X, Ma F, Gharaee-Kermani M, Kahlenberg JM, Harms PW, Maverakis E, Nie Q, Gudjonsson JE, Andersen B. Wiedemann J, et al. Cell Rep. 2023 Jan 31;42(1):111994. doi: 10.1016/j.celrep.2023.111994. Epub 2023 Jan 24. Cell Rep. 2023. PMID: 36732947 Free PMC article.
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.
Ma F, Plazyo O, Billi AC, Tsoi LC, Xing X, Wasikowski R, Gharaee-Kermani M, Hile G, Jiang Y, Harms PW, Xing E, Kirma J, Xi J, Hsu JE, Sarkar MK, Chung Y, Di Domizio J, Gilliet M, Ward NL, Maverakis E, Klechevsky E, Voorhees JJ, Elder JT, Lee JH, Kahlenberg JM, Pellegrini M, Modlin RL, Gudjonsson JE. Ma F, et al. Nat Commun. 2023 Jun 12;14(1):3455. doi: 10.1038/s41467-023-39020-4. Nat Commun. 2023. PMID: 37308489 Free PMC article.
Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis.
Xing E, Ma F, Wasikowski R, Billi AC, Gharaee-Kermani M, Fox J, Dobry C, Victory A, Sarkar MK, Xing X, Plazyo O, Chen HW, Barber G, Jacobe H, Tsou PS, Modlin RL, Varga J, Kahlenberg JM, Tsoi LC, Gudjonsson JE, Khanna D. Xing E, et al. Among authors: gharaee kermani m. JCI Insight. 2023 Aug 22;8(16):e171307. doi: 10.1172/jci.insight.171307. JCI Insight. 2023. PMID: 37471168 Free PMC article.
62 results