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Artificial Intelligence for COVID-19 Drug Discovery and Vaccine Development.
Front Artif Intell. 2020 Aug 18;3:65. doi: 10.3389/frai.2020.00065. eCollection 2020.
Front Artif Intell. 2020.
PMID: 33733182
Free PMC article.
Review.
DNA Sequence Control of Enzyme Filamentation and Activation of the SgrAI Endonuclease.
Ghadirian N, Morgan RD, Horton NC.
Ghadirian N, et al.
Biochemistry. 2024 Feb 6;63(3):326-338. doi: 10.1021/acs.biochem.3c00313. Epub 2024 Jan 11.
Biochemistry. 2024.
PMID: 38207281
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High-Resolution Structure of the Nuclease Domain of the Human Parvovirus B19 Main Replication Protein NS1.
Sanchez JL, Ghadirian N, Horton NC.
Sanchez JL, et al. Among authors: ghadirian n.
J Virol. 2022 May 11;96(9):e0216421. doi: 10.1128/jvi.02164-21. Epub 2022 Apr 18.
J Virol. 2022.
PMID: 35435730
Free PMC article.
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The Need for Speed: Run-On Oligomer Filament Formation Provides Maximum Speed with Maximum Sequestration of Activity.
Barahona CJ, Basantes LE, Tompkins KJ, Heitman DM, Chukwu BI, Sanchez J, Sanchez JL, Ghadirian N, Park CK, Horton NC.
Barahona CJ, et al. Among authors: ghadirian n.
J Virol. 2019 Feb 19;93(5):e01647-18. doi: 10.1128/JVI.01647-18. Print 2019 Mar 1.
J Virol. 2019.
PMID: 30518649
Free PMC article.
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Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity.
Shan Z, Ghadirian N, Lyumkis D, Horton NC.
Shan Z, et al. Among authors: ghadirian n.
J Biol Chem. 2022 Apr;298(4):101760. doi: 10.1016/j.jbc.2022.101760. Epub 2022 Feb 21.
J Biol Chem. 2022.
PMID: 35202658
Free PMC article.
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Physachenolide C is a Potent, Selective BET Inhibitor.
Zerio CJ, Sivinski J, Wijeratne EMK, Xu YM, Ngo DT, Ambrose AJ, Villa-Celis L, Ghadirian N, Clarkson MW, Zhang DD, Horton NC, Gunatilaka AAL, Fromme R, Chapman E.
Zerio CJ, et al. Among authors: ghadirian n.
J Med Chem. 2023 Jan 12;66(1):913-933. doi: 10.1021/acs.jmedchem.2c01770. Epub 2022 Dec 28.
J Med Chem. 2023.
PMID: 36577036
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Measurement of brain regional alpha-[11C]methyl-L-tryptophan trapping as a measure of serotonin synthesis in medication-free patients with major depression.
Rosa-Neto P, Diksic M, Okazawa H, Leyton M, Ghadirian N, Mzengeza S, Nakai A, Debonnel G, Blier P, Benkelfat C.
Rosa-Neto P, et al. Among authors: ghadirian n.
Arch Gen Psychiatry. 2004 Jun;61(6):556-63. doi: 10.1001/archpsyc.61.6.556.
Arch Gen Psychiatry. 2004.
PMID: 15184235
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