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Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade.
Gu SS, Zhang W, Wang X, Jiang P, Traugh N, Li Z, Meyer C, Stewig B, Xie Y, Bu X, Manos MP, Font-Tello A, Gjini E, Lako A, Lim K, Conway J, Tewari AK, Zeng Z, Sahu AD, Tokheim C, Weirather JL, Fu J, Zhang Y, Kroger B, Liang JH, Cejas P, Freeman GJ, Rodig S, Long HW, Gewurz BE, Hodi FS, Brown M, Liu XS. Gu SS, et al. Among authors: gewurz be. Cancer Discov. 2021 Jun;11(6):1524-1541. doi: 10.1158/2159-8290.CD-20-0812. Epub 2021 Feb 15. Cancer Discov. 2021. PMID: 33589424 Free PMC article.
Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses.
Shrock EL, Timms RT, Kula T, Mena EL, West AP Jr, Guo R, Lee IH, Cohen AA, McKay LGA, Bi C, Leng Y, Fujimura E, Horns F, Li M, Wesemann DR, Griffiths A, Gewurz BE, Bjorkman PJ, Elledge SJ. Shrock EL, et al. Among authors: gewurz be. Science. 2023 Apr 7;380(6640):eadc9498. doi: 10.1126/science.adc9498. Epub 2023 Apr 7. Science. 2023. PMID: 37023193 Free PMC article.
Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome.
Viel KCMF, Parameswaran S, Donmez OA, Forney CR, Hass MR, Yin C, Jones SH, Prosser HK, Diouf AA, Gittens OE, Edsall LE, Chen X, Rowden H, Dunn KA, Guo R, VonHandorf A, Leong MML, Ernst K, Kaufman KM, Lawson LP, Gewurz B, Zhao B, Kottyan LC, Weirauch MT. Viel KCMF, et al. BMC Genomics. 2024 Mar 12;25(1):273. doi: 10.1186/s12864-024-10183-8. BMC Genomics. 2024. PMID: 38475709 Free PMC article.
Elliott Dan Kieff, MD, PhD (1943-2024).
Raab-Traub N, Gewurz BE. Raab-Traub N, et al. Among authors: gewurz be. Cell. 2024 Apr 11;187(8):1819-1821. doi: 10.1016/j.cell.2024.02.038. Cell. 2024. PMID: 38608648 No abstract available.
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication.
Zhang Y, Guo R, Kim SH, Shah H, Zhang S, Liang JH, Fang Y, Gentili M, Leary CNO, Elledge SJ, Hung DT, Mootha VK, Gewurz BE. Zhang Y, et al. Among authors: gewurz be. Nat Commun. 2021 Mar 15;12(1):1676. doi: 10.1038/s41467-021-21903-z. Nat Commun. 2021. PMID: 33723254 Free PMC article.
Methionine metabolism controls the B cell EBV epigenome and viral latency.
Guo R, Liang JH, Zhang Y, Lutchenkov M, Li Z, Wang Y, Trujillo-Alonso V, Puri R, Giulino-Roth L, Gewurz BE. Guo R, et al. Among authors: gewurz be. Cell Metab. 2022 Sep 6;34(9):1280-1297.e9. doi: 10.1016/j.cmet.2022.08.008. Cell Metab. 2022. PMID: 36070681 Free PMC article.
Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma.
Wang C, Jiang S, Ke L, Zhang L, Li D, Liang J, Narita Y, Hou I, Chen CH, Wang L, Zhong Q, Ling Y, Lv X, Xiang Y, Guo X, Teng M, Tsao SW, Gewurz BE, Zeng MS, Zhao B. Wang C, et al. Among authors: gewurz be. J Biol Chem. 2019 Jun 21;294(25):9734-9745. doi: 10.1074/jbc.RA119.008793. Epub 2019 May 9. J Biol Chem. 2019. PMID: 31073033 Free PMC article.
87 results