Gerwick WH - Search Results

1

The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni.

Bibo-Verdugo B, Wang SC, Almaliti J, Ta AP, Jiang Z, Wong DA, Lietz CB, Suzuki BM, El-Sakkary N, Hook V, Salvesen GS, Gerwick WH, Caffrey CR, O'Donoghue AJ. Bibo-Verdugo B, et al. Among authors: gerwick wh. ACS Infect Dis. 2019 Oct 11;5(10):1802-1812. doi: 10.1021/acsinfecdis.9b00237. Epub 2019 Aug 12. ACS Infect Dis. 2019. PMID: 31355632 Free PMC article.

2

An aldehyde-containing galactolipid from the red alga Gracilariopsis lemaneiformis.

Jiang ZD, Gerwick WH. Jiang ZD, et al. Among authors: gerwick wh. Lipids. 1991 Nov;26(11):960-3. doi: 10.1007/BF02535985. Lipids. 1991. PMID: 1805099

3

Novel pyrroles from the Oregon red alga Gracilariopsis lemaneiformis.

Jiang ZD, Gerwick WH. Jiang ZD, et al. Among authors: gerwick wh. J Nat Prod. 1991 Mar-Apr;54(2):403-7. doi: 10.1021/np50074a009. J Nat Prod. 1991. PMID: 1919587

4

Novel oxylipins from the temperate red alga Polyneura latissima: evidence for an arachidonate 9(S)-lipoxygenase.

Jiang ZD, Gerwick WH. Jiang ZD, et al. Among authors: gerwick wh. Lipids. 1997 Mar;32(3):231-5. doi: 10.1007/s11745-997-0029-9. Lipids. 1997. PMID: 9076659

5

The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L.

Miller B, Friedman AJ, Choi H, Hogan J, McCammon JA, Hook V, Gerwick WH. Miller B, et al. Among authors: gerwick wh. J Nat Prod. 2014 Jan 24;77(1):92-9. doi: 10.1021/np400727r. Epub 2013 Dec 23. J Nat Prod. 2014. PMID: 24364476 Free PMC article.

6

Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel.

Paatero AO, Kellosalo J, Dunyak BM, Almaliti J, Gestwicki JE, Gerwick WH, Taunton J, Paavilainen VO. Paatero AO, et al. Among authors: gerwick wh. Cell Chem Biol. 2016 May 19;23(5):561-566. doi: 10.1016/j.chembiol.2016.04.008. Cell Chem Biol. 2016. PMID: 27203376 Free article.

7

Dudawalamides A-D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens.

Almaliti J, Malloy KL, Glukhov E, Spadafora C, Gutiérrez M, Gerwick WH. Almaliti J, et al. Among authors: gerwick wh. J Nat Prod. 2017 Jun 23;80(6):1827-1836. doi: 10.1021/acs.jnatprod.7b00034. Epub 2017 May 23. J Nat Prod. 2017. PMID: 28535042

8

Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity.

LaMonte GM, Almaliti J, Bibo-Verdugo B, Keller L, Zou BY, Yang J, Antonova-Koch Y, Orjuela-Sanchez P, Boyle CA, Vigil E, Wang L, Goldgof GM, Gerwick L, O'Donoghue AJ, Winzeler EA, Gerwick WH, Ottilie S. LaMonte GM, et al. Among authors: gerwick l, gerwick wh. J Med Chem. 2017 Aug 10;60(15):6721-6732. doi: 10.1021/acs.jmedchem.7b00671. Epub 2017 Jul 25. J Med Chem. 2017. PMID: 28696697 Free PMC article.

9

Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species.

Naman CB, Almaliti J, Armstrong L, Caro-Díaz EJ, Pierce ML, Glukhov E, Fenner A, Spadafora C, Debonsi HM, Dorrestein PC, Murray TF, Gerwick WH. Naman CB, et al. Among authors: gerwick wh. J Nat Prod. 2017 Aug 25;80(8):2328-2334. doi: 10.1021/acs.jnatprod.7b00367. Epub 2017 Aug 7. J Nat Prod. 2017. PMID: 28783331

10

Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.

Almaliti J, Miller B, Pietraszkiewicz H, Glukhov E, Naman CB, Kline T, Hanson J, Li X, Zhou S, Valeriote FA, Gerwick WH. Almaliti J, et al. Among authors: gerwick wh. Eur J Med Chem. 2019 Jan 1;161:416-432. doi: 10.1016/j.ejmech.2018.10.024. Epub 2018 Oct 15. Eur J Med Chem. 2019. PMID: 30384045 Free PMC article.

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