Gersting SW - Search Results

1

Specific CD4+ T Cell Responses to Ancestral SARS-CoV-2 in Children Increase With Age and Show Cross-Reactivity to Beta Variant.

Paul K, Sibbertsen F, Weiskopf D, Lütgehetmann M, Barroso M, Danecka MK, Glau L, Hecher L, Hermann K, Kohl A, Oh J, Schulze Zur Wiesch J, Sette A, Tolosa E, Vettorazzi E, Woidy M, Zapf A, Zazara DE, Mir TS, Muntau AC, Gersting SW, Dunay GA. Paul K, et al. Among authors: gersting sw. Front Immunol. 2022 Jul 15;13:867577. doi: 10.3389/fimmu.2022.867577. eCollection 2022. Front Immunol. 2022. PMID: 35911689 Free PMC article.

2

Loss of function in phenylketonuria is caused by impaired molecular motions and conformational instability.

Gersting SW, Kemter KF, Staudigl M, Messing DD, Danecka MK, Lagler FB, Sommerhoff CP, Roscher AA, Muntau AC. Gersting SW, et al. Am J Hum Genet. 2008 Jul;83(1):5-17. doi: 10.1016/j.ajhg.2008.05.013. Epub 2008 Jun 5. Am J Hum Genet. 2008. PMID: 18538294 Free PMC article.

3

Pahenu1 is a mouse model for tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency and promotes analysis of the pharmacological chaperone mechanism in vivo.

Gersting SW, Lagler FB, Eichinger A, Kemter KF, Danecka MK, Messing DD, Staudigl M, Domdey KA, Zsifkovits C, Fingerhut R, Glossmann H, Roscher AA, Muntau AC. Gersting SW, et al. Hum Mol Genet. 2010 May 15;19(10):2039-49. doi: 10.1093/hmg/ddq085. Epub 2010 Feb 23. Hum Mol Genet. 2010. PMID: 20179079 Free article.

4

Activation of phenylalanine hydroxylase induces positive cooperativity toward the natural cofactor.

Gersting SW, Staudigl M, Truger MS, Messing DD, Danecka MK, Sommerhoff CP, Kemter KF, Muntau AC. Gersting SW, et al. J Biol Chem. 2010 Oct 1;285(40):30686-97. doi: 10.1074/jbc.M110.124016. Epub 2010 Jul 27. J Biol Chem. 2010. PMID: 20667834 Free PMC article.

5

Phenylketonuria as a model for protein misfolding diseases and for the development of next generation orphan drugs for patients with inborn errors of metabolism.

Muntau AC, Gersting SW. Muntau AC, et al. Among authors: gersting sw. J Inherit Metab Dis. 2010 Dec;33(6):649-58. doi: 10.1007/s10545-010-9185-4. Epub 2010 Sep 8. J Inherit Metab Dis. 2010. PMID: 20824346 Review.

6

The interplay between genotype, metabolic state and cofactor treatment governs phenylalanine hydroxylase function and drug response.

Staudigl M, Gersting SW, Danecka MK, Messing DD, Woidy M, Pinkas D, Kemter KF, Blau N, Muntau AC. Staudigl M, et al. Among authors: gersting sw. Hum Mol Genet. 2011 Jul 1;20(13):2628-41. doi: 10.1093/hmg/ddr165. Epub 2011 Apr 28. Hum Mol Genet. 2011. PMID: 21527427 Free article.

7

Bioluminescence resonance energy transfer: an emerging tool for the detection of protein-protein interaction in living cells.

Gersting SW, Lotz-Havla AS, Muntau AC. Gersting SW, et al. Methods Mol Biol. 2012;815:253-63. doi: 10.1007/978-1-61779-424-7_19. Methods Mol Biol. 2012. PMID: 22130997

8

Innovative strategies to treat protein misfolding in inborn errors of metabolism: pharmacological chaperones and proteostasis regulators.

Muntau AC, Leandro J, Staudigl M, Mayer F, Gersting SW. Muntau AC, et al. Among authors: gersting sw. J Inherit Metab Dis. 2014 Jul;37(4):505-23. doi: 10.1007/s10545-014-9701-z. Epub 2014 Apr 1. J Inherit Metab Dis. 2014. PMID: 24687294 Review.

9

The domain-specific and temperature-dependent protein misfolding phenotype of variant medium-chain acyl-CoA dehydrogenase.

Jank JM, Maier EM, Reiβ DD, Haslbeck M, Kemter KF, Truger MS, Sommerhoff CP, Ferdinandusse S, Wanders RJ, Gersting SW, Muntau AC. Jank JM, et al. Among authors: gersting sw. PLoS One. 2014 Apr 9;9(4):e93852. doi: 10.1371/journal.pone.0093852. eCollection 2014. PLoS One. 2014. PMID: 24718418 Free PMC article.

10

Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production.

Roth S, Rottach A, Lotz-Havla AS, Laux V, Muschaweckh A, Gersting SW, Muntau AC, Hopfner KP, Jin L, Vanness K, Petrini JH, Drexler I, Leonhardt H, Ruland J. Roth S, et al. Among authors: gersting sw. Nat Immunol. 2014 Jun;15(6):538-45. doi: 10.1038/ni.2888. Epub 2014 Apr 28. Nat Immunol. 2014. PMID: 24777530 Free PMC article.

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