Gerson SL - Search Results

1

Clinical relevance of MGMT in the treatment of cancer.

Gerson SL. Gerson SL. J Clin Oncol. 2002 May 1;20(9):2388-99. doi: 10.1200/JCO.2002.06.110. J Clin Oncol. 2002. PMID: 11981013 Review.

2

Targeted modulation of MGMT: clinical implications.

Liu L, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 2006 Jan 15;12(2):328-31. doi: 10.1158/1078-0432.CCR-05-2543. Clin Cancer Res. 2006. PMID: 16428468 Review.

3

Modulation of O6-alkylguanine alkyltransferase-directed DNA repair in metastatic colon cancers.

Willson JK, Haaga JR, Trey JE, Stellato TA, Gordon NH, Gerson SL. Willson JK, et al. Among authors: gerson sl. J Clin Oncol. 1995 Sep;13(9):2301-8. doi: 10.1200/JCO.1995.13.9.2301. J Clin Oncol. 1995. PMID: 7666087 Clinical Trial.

4

Myeloablation is not required to select and maintain expression of the drug-resistance gene, mutant MGMT, in primary and secondary recipients.

Bowman JE, Reese JS, Lingas KT, Gerson SL. Bowman JE, et al. Among authors: gerson sl. Mol Ther. 2003 Jul;8(1):42-50. doi: 10.1016/s1525-0016(03)00141-2. Mol Ther. 2003. PMID: 12842427 Free article.

5

Limited lentiviral transgene expression with increasing copy number in an MGMT selection model: lack of copy number selection by drug treatment.

Zielske SP, Lingas KT, Li Y, Gerson SL. Zielske SP, et al. Among authors: gerson sl. Mol Ther. 2004 Jun;9(6):923-31. doi: 10.1016/j.ymthe.2004.02.017. Mol Ther. 2004. PMID: 15194059 Free article.

6

O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.

Phillips WP Jr, Willson JK, Markowitz SD, Zborowska E, Zaidi NH, Liu L, Gordon NH, Gerson SL. Phillips WP Jr, et al. Among authors: gerson sl. Cancer Res. 1997 Nov 1;57(21):4817-23. Cancer Res. 1997. PMID: 9354444

7

Base excision repair as a therapeutic target in colon cancer.

Liu L, Nakatsuru Y, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 2002 Sep;8(9):2985-91. Clin Cancer Res. 2002. PMID: 12231545

8

Differential degradation rates of inactivated alkyltransferase in blood mononuclear cells and tumors of patients after treatment with O(6)-benzylguanine.

Liu L, Spiro TP, Qin X, Majka S, Haaga J, Schupp J, Willson JK, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 2001 Aug;7(8):2318-24. Clin Cancer Res. 2001. PMID: 11489807

9

Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide.

Reese JS, Davis BM, Liu L, Gerson SL. Reese JS, et al. Among authors: gerson sl. Clin Cancer Res. 1999 Jan;5(1):163-9. Clin Cancer Res. 1999. PMID: 9918215

10

Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro.

Zielske SP, Gerson SL. Zielske SP, et al. Among authors: gerson sl. Mol Ther. 2002 Apr;5(4):381-7. doi: 10.1006/mthe.2002.0571. Mol Ther. 2002. PMID: 11945064 Free article.

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