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Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice.
Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2221894120. doi: 10.1073/pnas.2221894120. Epub 2023 Jun 12.
Proc Natl Acad Sci U S A. 2023.
PMID: 37307443
Free PMC article.
Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.
Schvartzman JM, Forsyth G, Walch H, Chatila W, Taglialatela A, Lee BJ, Zhu X, Gershik S, Cimino FV, Santella A, Menghrajani K, Ciccia A, Koche R, Sánchez-Vega F, Zha S, Thompson CB.
Schvartzman JM, et al. Among authors: gershik s.
Mol Cell. 2023 Jul 6;83(13):2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026. Epub 2023 Jun 12.
Mol Cell. 2023.
PMID: 37311462
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Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.
Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S.
Lin X, et al. Among authors: gershik s.
bioRxiv [Preprint]. 2024 Mar 14:2024.03.12.584665. doi: 10.1101/2024.03.12.584665.
bioRxiv. 2024.
PMID: 38559022
Free PMC article.
Preprint.
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Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner.
Shao Z, Lee BJ, Zhang H, Lin X, Li C, Jiang W, Chirathivat N, Gershik S, Shen MM, Baer R, Zha S.
Shao Z, et al. Among authors: gershik s.
Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2301972120. doi: 10.1073/pnas.2301972120. Epub 2023 Jul 24.
Proc Natl Acad Sci U S A. 2023.
PMID: 37487079
Free PMC article.
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ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.
Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S.
Menolfi D, et al. Among authors: gershik s.
Nat Commun. 2023 Jun 19;14(1):3618. doi: 10.1038/s41467-023-39332-5.
Nat Commun. 2023.
PMID: 37336885
Free PMC article.
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ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.
Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S.
Menolfi D, et al. Among authors: gershik s.
bioRxiv [Preprint]. 2023 May 27:2023.05.26.542515. doi: 10.1101/2023.05.26.542515.
bioRxiv. 2023.
PMID: 37292881
Free PMC article.
Updated.
Preprint.
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