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Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart.
Walejko JM, Christopher BA, Crown SB, Zhang GF, Pickar-Oliver A, Yoneshiro T, Foster MW, Page S, van Vliet S, Ilkayeva O, Muehlbauer MJ, Carson MW, Brozinick JT, Hammond CD, Gimeno RE, Moseley MA, Kajimura S, Gersbach CA, Newgard CB, White PJ, McGarrah RW. Walejko JM, et al. Among authors: gersbach ca. Nat Commun. 2021 Mar 15;12(1):1680. doi: 10.1038/s41467-021-21962-2. Nat Commun. 2021. PMID: 33723250 Free PMC article.
Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles.
Fletcher RB, Stokes LD, Kelly IB 3rd, Henderson KM, Vallecillo-Viejo IC, Colazo JM, Wong BV, Yu F, d'Arcy R, Struthers MN, Evans BC, Ayers J, Castanon M, Weirich MJ, Reilly SK, Patel SS, Ivanova YI, Silvera Batista CA, Weiss SM, Gersbach CA, Brunger JM, Duvall CL. Fletcher RB, et al. Among authors: gersbach ca. ACS Nano. 2023 Sep 12;17(17):16412-16431. doi: 10.1021/acsnano.2c12261. Epub 2023 Aug 15. ACS Nano. 2023. PMID: 37582231
The next generation of CRISPR-Cas technologies and applications.
Pickar-Oliver A, Gersbach CA. Pickar-Oliver A, et al. Among authors: gersbach ca. Nat Rev Mol Cell Biol. 2019 Aug;20(8):490-507. doi: 10.1038/s41580-019-0131-5. Nat Rev Mol Cell Biol. 2019. PMID: 31147612 Free PMC article. Review.
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells.
Pickar-Oliver A, Black JB, Lewis MM, Mutchnick KJ, Klann TS, Gilcrest KA, Sitton MJ, Nelson CE, Barrera A, Bartelt LC, Reddy TE, Beisel CL, Barrangou R, Gersbach CA. Pickar-Oliver A, et al. Among authors: gersbach ca. Nat Biotechnol. 2019 Dec;37(12):1493-1501. doi: 10.1038/s41587-019-0235-7. Epub 2019 Sep 23. Nat Biotechnol. 2019. PMID: 31548729 Free PMC article.
The once and future gene therapy.
Bulaklak K, Gersbach CA. Bulaklak K, et al. Among authors: gersbach ca. Nat Commun. 2020 Nov 16;11(1):5820. doi: 10.1038/s41467-020-19505-2. Nat Commun. 2020. PMID: 33199717 Free PMC article.
A humanized mouse model for adeno-associated viral gene therapy.
Barzi M, Chen T, Gonzalez TJ, Pankowicz FP, Oh SH, Streff HL, Rosales A, Ma Y, Collias S, Woodfield SE, Diehl AM, Vasudevan SA, Galvan TN, Goss J, Gersbach CA, Bissig-Choisat B, Asokan A, Bissig KD. Barzi M, et al. Among authors: gersbach ca. Nat Commun. 2024 Mar 4;15(1):1955. doi: 10.1038/s41467-024-46017-0. Nat Commun. 2024. PMID: 38438373 Free PMC article.
132 results