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Year Number of Results
2004 1
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2010 5
2011 6
2012 9
2013 10
2014 6
2015 5
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2017 2
2018 4
2019 1
2021 1
2022 3
2023 2
2024 0

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48 results

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Page 1
Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug-Drug Interactions in Rats.
Melillo N, Scotcher D, Kenna JG, Green C, Hines CDG, Laitinen I, Hockings PD, Ogungbenro K, Gunwhy ER, Sourbron S, Waterton JC, Schuetz G, Galetin A. Melillo N, et al. Among authors: kenna jg. Pharmaceutics. 2023 Mar 10;15(3):896. doi: 10.3390/pharmaceutics15030896. Pharmaceutics. 2023. PMID: 36986758 Free PMC article.
Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment.
Turner J, Pound P, Owen C, Hutchinson I, Hop M, Chau DYS, Barrios Silva LV, Coleman M, Dubourg A, Harries LW, Hutter V, Kenna JG, Lauschke VM, Neuhaus W, Roper C, Watkins PB, Welch J, Alvarez LR, Taylor K. Turner J, et al. Among authors: kenna jg. ALTEX. 2023;40(3):519-533. doi: 10.14573/altex.2212081. Epub 2023 Jan 18. ALTEX. 2023. PMID: 36692187 Free article.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Ouedraogo G, Alexander-White C, Bury D, Clewell HJ 3rd, Cronin M, Cull T, Dent M, Desprez B, Detroyer A, Ellison C, Giammanco S, Hack E, Hewitt NJ, Kenna G, Klaric M, Kreiling R, Lester C, Mahony C, Mombelli E, Naciff J, O'Brien J, Schepky A, Tozer S, van der Burg B, van Vugt-Lussenburg B, Stuard S, Cosmetics Europe. Ouedraogo G, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2022 Jul;132:105161. doi: 10.1016/j.yrtph.2022.105161. Epub 2022 May 1. Regul Toxicol Pharmacol. 2022. PMID: 35508214 Free article.
Use of in vitro metabolism and biokinetics assays to refine predicted in vivo and in vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use in risk assessment.
Hewitt NJ, Troutman J, Przibilla J, Schepky A, Ouédraogo G, Mahony C, Kenna G, Varçin M, Dent MP; Cosmetics Europe. Electronic address: cosmeticseurope@cosmeticseurope.eu. Hewitt NJ, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2022 Jun;131:105132. doi: 10.1016/j.yrtph.2022.105132. Epub 2022 Feb 22. Regul Toxicol Pharmacol. 2022. PMID: 35217105 Free article.
A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment.
Alexander-White C, Bury D, Cronin M, Dent M, Hack E, Hewitt NJ, Kenna G, Naciff J, Ouedraogo G, Schepky A, Mahony C, Europe C. Alexander-White C, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2022 Mar;129:105094. doi: 10.1016/j.yrtph.2021.105094. Epub 2022 Jan 4. Regul Toxicol Pharmacol. 2022. PMID: 34990780 Free article.
New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Bury D, Alexander-White C, Clewell HJ 3rd, Cronin M, Desprez B, Detroyer A, Efremenko A, Firman J, Hack E, Hewitt NJ, Kenna G, Klaric M, Lester C, Mahony C, Ouedraogo G, Paini A, Schepky A; Cosmetics Europe. Bury D, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2021 Jul;123:104931. doi: 10.1016/j.yrtph.2021.104931. Epub 2021 Apr 24. Regul Toxicol Pharmacol. 2021. PMID: 33905778 Free article.
Advancing nonclinical innovation and safety in pharmaceutical testing.
Baker EJ, Beck NA, Berg EL, Clayton-Jeter HD, Chandrasekera PC, Curley JL, Donzanti BA, Ewart LC, Gunther JM, Kenna JG, LeCluyse EL, Liebman MN, Pugh CL, Watkins PB, Sullivan KM. Baker EJ, et al. Among authors: kenna jg. Drug Discov Today. 2019 Feb;24(2):624-628. doi: 10.1016/j.drudis.2018.11.011. Epub 2018 Nov 20. Drug Discov Today. 2019. PMID: 30468877 Free article. Review.
Better science for safer medicines: the human imperative.
Archibald K, Tsaioun K, Kenna JG, Pound P. Archibald K, et al. Among authors: kenna jg. J R Soc Med. 2018 Dec;111(12):433-438. doi: 10.1177/0141076818812783. Epub 2018 Nov 15. J R Soc Med. 2018. PMID: 30439294 Free PMC article. No abstract available.
Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective.
Kenna JG, Taskar KS, Battista C, Bourdet DL, Brouwer KLR, Brouwer KR, Dai D, Funk C, Hafey MJ, Lai Y, Maher J, Pak YA, Pedersen JM, Polli JW, Rodrigues AD, Watkins PB, Yang K, Yucha RW; International Transporter Consortium. Kenna JG, et al. Clin Pharmacol Ther. 2018 Nov;104(5):916-932. doi: 10.1002/cpt.1222. Clin Pharmacol Ther. 2018. PMID: 30137645 Free PMC article. Review.
48 results