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Structure-based design of protein tyrosine phosphatase-1B inhibitors.
Black E, Breed J, Breeze AL, Embrey K, Garcia R, Gero TW, Godfrey L, Kenny PW, Morley AD, Minshull CA, Pannifer AD, Read J, Rees A, Russell DJ, Toader D, Tucker J. Black E, et al. Among authors: gero tw. Bioorg Med Chem Lett. 2005 May 16;15(10):2503-7. doi: 10.1016/j.bmcl.2005.03.068. Bioorg Med Chem Lett. 2005. PMID: 15863305
Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors.
Janetka JW, Almeida L, Ashwell S, Brassil PJ, Daly K, Deng C, Gero T, Glynn RE, Horn CL, Ioannidis S, Lyne P, Newcombe NJ, Oza VB, Pass M, Springer SK, Su M, Toader D, Vasbinder MM, Yu D, Yu Y, Zabludoff SD. Janetka JW, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4242-8. doi: 10.1016/j.bmcl.2008.05.016. Epub 2008 May 6. Bioorg Med Chem Lett. 2008. PMID: 18547806
3-amido-4-anilinocinnolines as a novel class of CSF-1R inhibitor.
Scott DA, Dakin LA, Del Valle DJ, Diebold RB, Drew L, Gero TW, Ogoe CA, Omer CA, Repik G, Thakur K, Ye Q, Zheng X. Scott DA, et al. Among authors: gero tw. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1382-4. doi: 10.1016/j.bmcl.2011.01.033. Epub 2011 Jan 14. Bioorg Med Chem Lett. 2011. PMID: 21295474
Towards the next generation of dual Bcl-2/Bcl-xL inhibitors.
Varnes JG, Gero T, Huang S, Diebold RB, Ogoe C, Grover PT, Su M, Mukherjee P, Saeh JC, MacIntyre T, Repik G, Dillman K, Byth K, Russell DJ, Ioannidis S. Varnes JG, et al. Bioorg Med Chem Lett. 2014 Jul 15;24(14):3026-33. doi: 10.1016/j.bmcl.2014.05.036. Epub 2014 May 20. Bioorg Med Chem Lett. 2014. PMID: 24881567
Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C.
Zeng M, Lu J, Li L, Feru F, Quan C, Gero TW, Ficarro SB, Xiong Y, Ambrogio C, Paranal RM, Catalano M, Shao J, Wong KK, Marto JA, Fischer ES, Jänne PA, Scott DA, Westover KD, Gray NS. Zeng M, et al. Among authors: gero tw. Cell Chem Biol. 2017 Aug 17;24(8):1005-1016.e3. doi: 10.1016/j.chembiol.2017.06.017. Epub 2017 Aug 3. Cell Chem Biol. 2017. PMID: 28781124 Free article.
Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors.
Grimster NP, Anderson E, Alimzhanov M, Bebernitz G, Bell K, Chuaqui C, Deegan T, Ferguson AD, Gero T, Harsch A, Huszar D, Kawatkar A, Kettle JG, Lyne P, Read JA, Rivard Costa C, Ruston L, Schroeder P, Shi J, Su Q, Throner S, Toader D, Vasbinder M, Woessner R, Wang H, Wu A, Ye M, Zheng W, Zinda M. Grimster NP, et al. J Med Chem. 2018 Jun 28;61(12):5235-5244. doi: 10.1021/acs.jmedchem.8b00076. Epub 2018 Jun 13. J Med Chem. 2018. PMID: 29856615
23 results